Beste apotheek van Nederland

Recommendations

Info

concurrent clinical conditions). There is also a need for trials comparing PDE–5 inhibitors withother treatments for ED (e.g. oral, injected and topical). Long-term effects of ED treatments inRCTs have not been adequately explored. To clarify and determine the clinical utility of routinehormonal blood tests in ED patients, studies are needed in representative populations, withcomparable diagnostic criteria and types of tests for hormonal disorders.7
Evidence Report
Page 1 and 2: This report is based on research co
Page 3 and 4: This document is in the public doma
Page 5 and 6: AcknowledgmentsThe authors would li
Page 7 and 8: ContentsExecutive Summary..........
Page 9 and 10: Table 17: Intra-urethral Treatment:
Page 11 and 12: Figure 63. Absolute Mean Change Fro
Page 13 and 14: associated with ED treatments. Two
Page 15 and 16: ED as a main complaint. In only one
Page 17: different formulations/modes of app
Page 21 and 22: flaccidity are no less important th
Page 23 and 24: prostatectomy, antipsychotic agents
Page 25 and 26: disease). Furthermore, there is ins
Page 27: Analytic FrameworkFigure 1. Analyti
Page 30 and 31: KQ 3. Harms of pharmaceutical treat
Page 32 and 33: Figure 2. Modified QUOROM Flow Char
Page 34 and 35: that included intervention characte
Page 36 and 37: Prevalence of Hypogonadism (Total S
Page 38 and 39: stimulation and a challenge test wi
Page 40 and 41: Overview of Trials79-84,86-88,90,91
Page 42 and 43: 131,137,138,142,143,147,151,155,156
Page 44 and 45: pectoris occurred in a participant
Page 46 and 47: statistical test results for the ob
Page 48 and 49: individual Q1-Q15 items, 104,106,15
Page 50 and 51: Proportion of participants with hea
Page 52 and 53: erectile maintenance frequency, IIE
Page 54 and 55: Oral Treatments — Phosphodiestera
Page 56 and 57: Patients were instructed to take th
Page 58 and 59: Results obtained from two trials 19
Page 60 and 61: improved erections was higher in pa
Page 62 and 63: Clinically homogenous groups of pat
Page 64 and 65: Oral Treatments — Phosphodiestera
Page 66 and 67: The approximate proportion of smoke
Page 68 and 69:
value was not reported). Even thoug
Page 70 and 71:
Tadalafil (20 mg) versus tadalafil
Page 72 and 73:
scheduled dosing regimen (90 percen
Page 74 and 75:
Proportion of patients with improve
Page 76 and 77:
Sublingual Treatments - Apomorphine
Page 78 and 79:
been taking over the past two or fo
Page 80 and 81:
apomorphine (5 and 6 mg: 38 and 49
Page 82 and 83:
heterogeneity with respect to popul
Page 84 and 85:
Finally, two studies reported on wh
Page 86 and 87:
the second study, prolonged erectio
Page 88 and 89:
Moxisylate versus placebo. One tria
Page 90 and 91:
Quantitative SynthesisThere was a l
Page 92 and 93:
erection” versus one placebo trea
Page 94 and 95:
methods of allocation concealment.
Page 96 and 97:
Prazosin (IU) versus placebo. One t
Page 98 and 99:
reported adequate allocation concea
Page 101 and 102:
Hormonal Treatments Literature Sear
Page 103 and 104:
Harms. In the first trial, the diff
Page 105 and 106:
sex with partner (scale 1-6, with =
Page 107 and 108:
daily for 4 weeks followed by concu
Page 109 and 110:
(MEDQoL) score (range 0-100) compar
Page 111 and 112:
group (16.7, 12.5, and 8.3 percent,
Page 113 and 114:
Question 3a. What Are the harms of
Page 115 and 116:
Chapter 4. DiscussionThis evidence
Page 117 and 118:
Question 1: What is the Clinical Ut
Page 119 and 120:
Questions 2-3: What are the Benefit
Page 121 and 122:
Harms. There were no obvious differ
Page 123 and 124:
alone. Compared with trimix alone,
Page 125 and 126:
PhentolamineEfficacy. The results i
Page 127 and 128:
Question 2a-b: Do Specific Patient
Page 129 and 130:
Methodological and Logistic Limitat
Page 131:
Tables and Figures.Summary TablesTa
Page 135:
123Study details 1 Study Design Set
Page 139:
125Table 2: Prevalence of Hypogonad
Page 143:
127Study Details 2 Study Design Set
Page 147:
129Table 4: Prevalence of Hypogonad
Page 151:
131Study Details 5 Study Design Set
Page 155:
Table 7: Prevalence of Hyperprolact
Page 159:
135StudyEDDetails 8 Study Design Se
Page 163 and 164:
Table 10: Serious Adverse Events in
Page 165 and 166:
Table 11: Efficacy Results of Tadal
Page 167 and 168:
Treatment Control Relative RiskStud
Page 169 and 170:
Treatment Control Relative RiskStud
Page 171 and 172:
Table 14: Intracavernosal Injection
Page 173 and 174:
StudyAdverse EventsTreatmentGroup%
Page 175 and 176:
StudyAdverse EventsTreatment Contro
Page 177 and 178:
Study / Typeof PatientsOutcome Defi
Page 179 and 180:
Study ED Etiology OutcomeWilliams*1
Page 181 and 182:
Physiologic:60.0 (18/30) 90.0 (27/3
Page 183 and 184:
StudyAdverse EventTreatmentGroup% (
Page 185 and 186:
TreatmentStudy ED Etiology Group% (
Page 187 and 188:
StudyAdverse EventCavallini 1991 Pa
Page 189 and 190:
Study/patient CharacteristicsGooma
Page 191 and 192:
Aversa 2003Men witharteriogenicEDYa
Page 193 and 194:
Study/patientCharacteristicsClopper
Page 195 and 196:
Study/patientCharacteristicsOutcome
Page 197 and 198:
Table 26: Testosterone Treatment: P
Page 199 and 200:
McNicholas2002Patients reporting
Page 201:
175Table 27: Miscellaneous Treatmen
Page 205:
177Table 28: Nonarteritic Anterior
Page 209 and 210:
Table 29: Penile Fibrosis in Studie
Page 211 and 212:
StudyStudyDesignPatientsage range 4
Page 213 and 214:
Figure 6. Improved erection (GEQ-Q1
Page 215 and 216:
Figure 11. Visual disturbances (all
Page 217 and 218:
Figure 16. Any adverse events (trea
Page 219 and 220:
Figure 23. The mean IIEF-Q4 score:
Page 221 and 222:
Figure 30. Improved erection (GEQ-Q
Page 223 and 224:
Figure 37. Visual disturbances (all
Page 225 and 226:
Figure 43. IIEF-EF ≥ 26 at follow
Page 227 and 228:
Figure 49. Dyspepsia (all cause)Fig
Page 229 and 230:
Figure 55. Serious adverse events (
Page 231 and 232:
Figure 61. Mean per-patient percent
Page 233 and 234:
Figure 67. Any adverse events (all-
Page 235 and 236:
Figure 73. Any adverse events (all-
Page 237 and 238:
in men with erectile dysfunction. J
Page 239 and 240:
parameters in obese men with erecti
Page 241 and 242:
comparative crossover study. Androl
Page 243 and 244:
153. Shabsigh R. Efficacy of silden
Page 245 and 246:
190.191.Stief C, Porst H, Saenz dT,
Page 247 and 248:
treatment of men with erectile dysf
Page 249 and 250:
randomized trial. J Urol 1997 Oct;1
Page 251 and 252:
moderate and severe ED. Int J Impot
Page 253 and 254:
349.350.351.randomized, placebo-con
Page 255 and 256:
395. Moher D, Schulz KF, Altman DG.
Page 257 and 258:
PSVRCTRIRIASBPSCSDSETTGTRTWMDpeak s
Page 259 and 260:
dDegDept.Ff/uFHxhrHxIGMmaxminmoNANI
Page 261 and 262:
30. or/24-2931. (ANIMALS not HUMAN)
Page 263 and 264:
27. limit 26 to yr="1990 - 2008"28.
Page 265 and 266:
5. exp clinical trials/6. random$.m
Page 267 and 268:
20. or/17-1921. 16 and 2022. limit
Page 269 and 270:
A systematic review of harms associ
Page 271:
B-4Summary Table- Randomized Contro
Page 274 and 275:
The Quality Assessment of Studies o
Page 277:
AuthorFundingN; study design; eligi
Page 281:
Page 285:
Page 289:
Page 293:
C-10 AuthorFundingN; study design;
Page 297:
Page 301:
Page 305:
Page 309:
Page 313:
Page 317:
Page 321:
Page 325:
Page 329:
Page 333:
Page 337:
Page 341:
Page 345:
Page 349:
Page 353:
Page 357:
Page 361:
Page 365:
Page 369:
Page 373:
Page 377:
Page 381:
Page 385:
Page 389:
Page 393:
Page 397:
Page 401:
Page 405:
Page 409:
Page 413:
Page 417:
Page 421:
Page 425:
Page 429:
Page 433:
Page 437:
Page 441:
Page 445:
Page 449:
Page 453:
Page 457:
Page 461:
Page 465:
Page 469:
Page 473:
Page 477:
Page 481:
Page 485:
Page 489:
Page 493:
Page 497:
Page 501:
Page 505:
Page 509:
Page 513:
Page 517:
Page 521:
Page 525:
Page 529:
Page 533:
Page 537:
Page 541:
Page 545:
Page 549:
Page 553:
Page 557:
Page 561:
Page 565:
C-146 C5-Intracavernousal Injection
Page 569:
Page 573:
Page 577:
Page 581:
Page 585:
Page 589:
Page 593:
Page 597:
Page 601:
Page 605:
Page 609:
Page 613:
Page 617:
Page 621:
Page 625:
Page 629:
Page 633:
Page 637:
Page 641:
Page 645:
Page 649:
Page 653:
Page 657:
Page 661:
Page 665:
Page 669:
Page 673:
Page 677:
C-202 C8-Topical Treatments of ED A
Page 681:
Page 685:
Page 689:
Page 693:
Page 697:
Page 701:
Page 705:
C-216 C9-Testosterone Treatment of
Page 709:
Page 713:
Page 717:
Page 721:
Page 725:
Page 729:
Page 733:
Page 737:
Page 741:
Page 745:
Page 749:
Page 753:
Page 757:
Page 761:
Page 765:
Page 769:
Page 773:
Page 777:
Page 781:
Page 785:
Page 788 and 789:
men with erectile dysfunction and s
Page 790 and 791:
symptoms associated with benign pro
Page 792 and 793:
(84) Zinner N. Do food and dose tim
Page 794 and 795:
(117) Carrier S, Brock GB, Pommervi
Page 796 and 797:
(150) Hagemann JH, Berding G, Bergh
Page 798 and 799:
(183) Moriel EZ, Rajfer J. Sodium b
Page 800 and 801:
(219) Gomaa A, Shalaby M, Osman M e
Page 802 and 803:
(255)(256)dysfunction. Psychopharma
Page 804 and 805:
Adams Henry E, Motsinger Patrice, M
Page 806 and 807:
Althof S E, Turner L A, Levine S B
Page 808 and 809:
Anonymous. Surgery & watchful waiti
Page 810 and 811:
Baker Christine D. A cognitive-beha
Page 812 and 813:
Bayes M, Rabasseda X, Prous J R. Ga
Page 814 and 815:
Bhatnagar V, Stewart S T, Huynh V e
Page 816 and 817:
Boswell-Smith V, Spina D, Page C P.
Page 818 and 819:
Burke J P, Jacobson D J, McGree M E
Page 820 and 821:
Carson C C. Combination of phosphod
Page 822 and 823:
Chen Y. Acupuncture treatment of fu
Page 824 and 825:
Cooke B M, Breedlove S M, Jordan C
Page 826 and 827:
Daitch J A, Angermeier K W, Lakin M
Page 828 and 829:
Derouet H, Jost W H, Osterhage J et
Page 830 and 831:
Doust J, Miller E, Duchesne G et al
Page 832 and 833:
Elhilali M M. Alfuzosin: An a1-rece
Page 834 and 835:
Ferri C, Giuggioli D, Cazzato M et
Page 836 and 837:
Frucht S J. Parkinson disease: An u
Page 838 and 839:
Ghofrani H A, Pepke-Zaba J, Barbera
Page 840 and 841:
Baldwin D S. Sexual dysfunction ass
Page 842 and 843:
Douglass M A, Lin J C. Update on th
Page 844 and 845:
Hatch J P. Psychophysiological aspe
Page 846 and 847:
Lau D H, Mumtaz F H, Thompson C S e
Page 848 and 849:
Morales A, Heaton J P. Hormonal ere
Page 850 and 851:
Roehrborn C G, McNicholas T. The Ma
Page 852 and 853:
Uckert S, Stief C G, Jonas U. Curre
Page 854 and 855:
Leungwattanakij S, Flynn V, Hellstr
Page 856 and 857:
Musacchio Najah S, Hartrich Molly,
Page 858 and 859:
Akkus E, Kadioglu A, Esen A et al.
Page 860 and 861:
Ashok S, Sigman M. Bioavailable tes
Page 862 and 863:
Briganti A, Salonia A, Gallina A et
Page 864 and 865:
Chinegwundoh F, Anie K A. Treatment
Page 866 and 867:
Dundar S O. Visual loss associated
Page 868 and 869:
Giammusso B, Gattuso U, Vanaclocha
Page 870 and 871:
Hawton Keith, Catalan Jose, Fagg Jo
Page 872 and 873:
Kell P. Cardiovascular safety of si
Page 874 and 875:
Laumann Edward O, West Suzanne, Gla
Page 876 and 877:
Matthew A G, Goldman A, Trachtenber
Page 878 and 879:
Mulhall J P. Deciphering erectile d
Page 880 and 881:
Parsons J K, Marschke P, Maples P e
Page 882 and 883:
Rojewski M T, Korper S, Schrezenmei
Page 884 and 885:
Shabsigh R. Testosterone therapy in
Page 886 and 887:
Tam S W, Worcel M, Wyllie M. Yohimb
Page 888 and 889:
Webb D J, Freestone S, Allen M J et
Page 890 and 891:
Katlowitz N M, Albano G J, Morales
Page 892 and 893:
Sparwasser C, Treiber U, Bahren W e
Page 894 and 895:
van Basten J P, Van Driel M F, Jonk
Page 896 and 897:
Youssef A F, Fort F L, Ronsen B et
Page 898 and 899:
Cooper A J. Evaluation of I-C papav
Page 900 and 901:
Isidori A M, Giannetta E, Gianfrill
Page 902 and 903:
Armstrong D K, Convery A, Dinsmore
Page 904 and 905:
Buvat J, Montorsi F. Safety and tol
Page 906 and 907:
De Rose A F, Giglio M, Traverso P e
Page 908 and 909:
Gana T E, Quizanos L F, Castell R e
Page 910 and 911:
Hatzichristou D G, Apostolidis A, T
Page 912 and 913:
Kim E D, McVary K T. Topical prosta
Page 914 and 915:
Lundberg L, Olsson J-O, Kihl B. Lon
Page 916 and 917:
Moncada I, Jara J, Subira D et al.
Page 918 and 919:
Ohebshalom M, Parker M, Guhring P e
Page 920 and 921:
Rajpurkar A, Dhabuwala C B. Compari
Page 922 and 923:
Shabsigh R. Hypogonadism and erecti
Page 924 and 925:
Terradas C, Levalle O, Nagelberg A
Page 926 and 927:
Yenicerioglu Y, Kefi A, Aslan G et
Page 928 and 929:
Anonymous. New erectile dysfunction
Page 930 and 931:
Bolona E R, Uraga M V, Haddad R M e
Page 932 and 933:
Chen J, Greenstein A, Kaver I et al
Page 934 and 935:
Derby C A, Barbour M M, Hume A L et
Page 936 and 937:
Foulks C J, Cushner H M. Sexual dys
Page 938 and 939:
Hamed S, Mohamed K, El-taher A et a
Page 940 and 941:
Jeong S-J, Park K, Moon J-D et al.
Page 942 and 943:
La Pera G, Franco Giannotti C, Tagg
Page 944 and 945:
Mann R D. Introduction - Tadalafil.
Page 946 and 947:
Montorsi F, Burnett A L. Erectile d
Page 948 and 949:
Ozdel O, Oguzhanoglu A, Oguzhanoglu
Page 950 and 951:
Ramasubbu Rajamannar. Switching to
Page 952 and 953:
Schwartz E J, Wong P, Graydon R J.
Page 954 and 955:
Stolk E A, Busschbach J J, Caffa M
Page 956 and 957:
Vitezic D. A risk-benefit assessmen
Page 958 and 959:
Bancroft J, Smith G, Munoz M et al.
Page 960 and 961:
Knispel H H, Huland H. Influence of
Page 962 and 963:
Padma-Nathan H, Eardley I, Kloner R
Page 964 and 965:
Bai W J, Zhu J C, Jiang H et al. [A
Page 966 and 967:
Carosa E, Martini P, Brandetti F et
Page 968 and 969:
Doggrell S A. Comparison of clinica
Page 970 and 971:
Gingell C, Buvat J, Jardin A et al.
Page 972 and 973:
Heaton J P, Morales A, Adams M A et
Page 974 and 975:
Kloner R A, Mitchell M, Emmick J T.
Page 976 and 977:
Marks L S, Duda C, Dorey F J et al.
Page 978 and 979:
Montorsi F, Guazzoni G, Bergamaschi
Page 980 and 981:
Padma-Nathan H, Goldstein I, Klimbe
Page 982 and 983:
Reznik I, Zemishlany Z, Kotler M et
Page 984 and 985:
Shamloul Rany, Kamel Ihab, E-Mail A
Page 986 and 987:
Tsujimura A, Yamanaka M, Takahashi
Page 988 and 989:
Zippe C D, Kedia A W, Kedia K et al
Page 990 and 991:
Anonymous. Diagnostic and therapeut
Page 992 and 993:
Briganti A, Chun F K H, Salonia A e
Page 994 and 995:
Clough J. CNS-targeted sexual dysfu
Page 996 and 997:
Emilien G. Alprox-TD NexMed Inc. Cu
Page 998 and 999:
Gryglewska B, Grodzicki T. Betaxolo
Page 1000 and 1001:
Kadioglu A, Erdogru T, Tellaloglu S
Page 1002 and 1003:
Lebret T, Herve J M, Gorny P et al.
Page 1004 and 1005:
Mealy N E. GPI-1485. Drugs of the F
Page 1006 and 1007:
O'Sullivan J D. Apomorphine as an a
Page 1008 and 1009:
Riley Alan. Oral treatments for ere
Page 1010 and 1011:
Silvestri A, Galetta P, Cerquetani
Page 1012 and 1013:
Unnikrishnan A G, Rajaratnam S, Ses
Page 1014 and 1015:
Zhao L. Clinical observation on the
Page 1016 and 1017:
The UO-EPC gratefully acknowledges
Page 1018 and 1019:
AuthorYearHellstrom 2005 37 Jadad Q
Page 1020 and 1021:
AuthorYearJadad Q-1 Jadad Q-2 Jadad
Page 1022 and 1023:
AuthorTotal AllocationJadad Q-1 Jad
Page 1024 and 1025:
AuthorYearSaylan 2006 265 Jadad Q-1
Page 1027:
F-10STUDY IDQ1:SpectrumQ2.Selection
Page 1030 and 1031:
Figure G-2. Sildenafil (any dose) v
Page 1032 and 1033:
Page 1034 and 1035:
Page 1036 and 1037:
Figure G-8. Sildenafil (25 mg) vs.
Page 1038 and 1039:
Figure G-10. Vardenafil (any dose)
Page 1040 and 1041:
Tadalfil20 mg vs. PlaceboFigure G-1
Page 1042 and 1043:
Figure G-14. Tadalafil (20 mg) vs.
Page 1044 and 1045:
Figure G-16. Tadalafil (20mg) vs. T
Page 1046 and 1047:
5 = Eleven+ attempts Q7: When you a
Page 1048 and 1049:
The IIEF-5 score is the sum of ques
Page 1050:
El Malik EMA. Erectile dysfunction:
show all

Beste apotheek van Nederland

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?