Mass Spectrometry - Faculté de médecine de l'université d'Ottawa

4 - 5.5 kV
ESI
solution
-
+
+ + +
+ + + + + + + +
- -
+
-
- -
- - -
- - -
Flow of gas (N 2 or air) nebulizing
the solution being electrosprayed
+ +
+
+ +
+ +
+ +
+
-
ESI droplets
++
+
+ +
+ +-
++ + +
+ +-
++ + +
+ +-
+
+
0 - 1 kV
+ +
+ + +
+ +
+ + + + +
+ + + +
+
+ + + ++ +
+ +
Mass
spectrometer
Schematic diagram of ionspray, or pneumatically-assisted electrospray ionization. The Taylor cone is
nebulized with N2 or air, aiding droplet formation and desolvation and allowing for a more stable spray
and higher flow rates.
11/21/2005 20