Lentiviral Vectors: design, production, and titration
Lentiviral Vectors: design, production, and titration
Lentiviral Vectors: design, production, and titration
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<strong>Lentiviral</strong> Vector System (3 rd generation)<br />
DU3 R U5<br />
Transgene<br />
Insertion of a heterologous Intron<br />
IRES<br />
∆U3 R U5<br />
A heterologous intron had been found to increase expression of transgenes<br />
in transgenic mice.<br />
DU3 R U5<br />
Intron<br />
Transgene<br />
Rat insulin II intron A<br />
2 nd<br />
promoter<br />
∆U3 R U5