Lentiviral Vectors: design, production, and titration
Lentiviral Vectors: design, production, and titration
Lentiviral Vectors: design, production, and titration
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Replication Competent Lentivirus (RCL)<br />
3 rd Generation <strong>Lentiviral</strong> Vector<br />
HIV provirus<br />
Wild-Type Virus<br />
LTR<br />
SD ψ<br />
Gag<br />
Pro<br />
Pol<br />
+ Replication competent LTR<br />
Vif<br />
Gag,pol, rev, env, tat<br />
R<br />
U<br />
Source:<br />
Carry over from packaging or<br />
Envelope plasmids<br />
Or<br />
Endogenous viruses<br />
Tat<br />
Rev<br />
RRE<br />
Env<br />
Nef<br />
LTR
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