Lentiviral Vectors: design, production, and titration
Lentiviral Vectors: design, production, and titration
Lentiviral Vectors: design, production, and titration
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<strong>Lentiviral</strong> Vector System<br />
2. Modification of 3’LTR “Self Inactivating”<br />
-456 +1 +60 +181<br />
U3 R U5<br />
-418<br />
EcoRV<br />
AP-1<br />
NF-AT?<br />
USF NF-κB<br />
Ets NF-ATc<br />
TCF-1α<br />
400 bp Deletion<br />
SP1<br />
TATA<br />
-18<br />
PvuII<br />
Wild-Type HIV 3’ LTR<br />
∆U3 R U5<br />
pHR’ SIN-18
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