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Antibiotic Classification and Modes of Action - bioMerieux

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Customer Education <strong>Antibiotic</strong> <strong>Classification</strong><br />

2. Inhibitors <strong>of</strong> Protein Synthesis<br />

Protein Synthesis<br />

Proteins are made up <strong>of</strong> at least 20 different amino<br />

acids<br />

AA<br />

AA AA<br />

AAAA<br />

Thous<strong>and</strong>s <strong>of</strong> different proteins exist, each with its<br />

own function (enzymes, etc.).<br />

Each protein is manufactured in the cell using a code<br />

contained in the DNA. DNA<br />

• The code for the 20 essential amino acids consists <strong>of</strong> at least a 3-base set<br />

(triplet) <strong>of</strong> the 4 bases<br />

• If one considers the possibilities <strong>of</strong> arranging four things 3 at a time<br />

(4X4X4), we get 64 possible code words, or codons (a 3-base sequence<br />

on the mRNA that codes for either a specific amino acid or a control<br />

sequence).<br />

AA<br />

© bioMérieux, Inc., Customer Education<br />

March 2008<br />

AA<br />

AA<br />

52

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