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Pratique C L I N I Q U E Chondrosarcoma of the Mandible: A Case Report Rajan Saini, BDS, MDS; Noor Hayati Abd Razak, BDS, M Clin Dent; Shiafulizan Ab Rahman, BDS, M Clin Dent; Abdul Rani Samsudin, BDS, FDSRCS, AM SOMMAIRE Les chondrosarcomes sont des tumeurs malignes d’origine cartilagineuse, qui varient de tumeurs bien différenciées ressemblant à une tumeur bénigne du cartilage à des tumeurs de haut grade de malignité affi chant un comportement local agressif et un potentiel métastatique. De 5 % à 10 % seulement des chondrosarcomes se manifestent dans la région de la tête et du cou. Nous présentons le cas d’un chondrosarcome siégeant dans la partie antérieure de la mandibule, et passons en revue la littérature pertinente. Mots clés MeSH : chondrosarcoma/pathology; female; mandibular neoplasms/pathology Pour les citations, la version définitive de cet article est la version électronique : www.cda-adc.ca/jcda/vol-73/issue-2/175.html Chondrosarcomas are malignant mesenchymal tumours with cartilaginous differentiation that only rarely affect the maxillofacial region. 1 Most chondrosarcomas of the head and neck region arise from the maxilla, with relatively few arising from the mandible. 2 Although chondrosarcoma occurs in patients of all ages, most of those a ected are over 50 years of age. 3 In most cases, the tumour presents as a painless mass or swelling associated with loosening of the associated teeth. is article describes a patient with chondrosarcoma of the anterior mandibular region. e clinical, radiographic, surgical and pathological aspects of this lesion are presented, and the relevant literature is reviewed. Case Report A 43-year-old woman was referred to a university-based dental clinic with swelling over the lingual aspect of the anterior mandible. e swelling had been present for 2 years and had increased gradually in size over that period. e patient denied any trauma or pain but reported di culty with swallowing solid foods. She had Auteur-ressource Dr Saini Courriel : rajan@ kb.usm.my asthma but was not taking any medication for this condition. Extraoral examination did not reveal any obvious facial swelling or asymmetry. ere was no cervical lymphadenopathy, and all of the cranial nerves were intact. Intraoral examination revealed an indurated, painless, discoid swelling about 2.5 cm × 2 cm in the midline of the anterior mandible between the lower incisors and the opening of the sublingual ducts. e overlying mucosa was pink and appeared normal. e anterior margin of the swelling was con uent with the lower alveolus. Intraoral, occlusal (Fig. 1) and panoramic radiographs revealed a radiolucent lesion with di use margins, which had displaced the roots of the central incisors. Computed tomography showed an expansile lytic lesion involving the symphysis menti and the body of the mandible (Fig. 2). inning of the cortex was observed, and there was evidence of a cortical break. ree-dimensional imaging showed destruction of bone at the mid-mandibular region (Fig. 3). Histopathological examination revealed chondrocytes in lacunae that were arranged JADC • www.cda-adc.ca/jadc • Mars 2007, Vol. 73, N o 2 • 175
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PM40064661 R10597 JOURNAL DE L'ASSO
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Directeur général de l’ADC Geor
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TA B L E D E S M AT I È R E S 139
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T A B L E D E S M A T I È R E S SU
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