saqarTvelos samedicino Jurnali Medical Journal of Georgia

12kardiologiahormonCanacvlebiTi Terapiis gavlena ekgparametrebze postmenopauzis drosav. isakaZe, m. noniaSviliq. Tbilisis #1 samkurnalo-profilaqtikuri centri,Tbilisis saxelmwifo samedicino universitetis Sinaganimedicinis #1 departamenti (mimarTuleba – Terapiasindromuli diagnostika)(recenzenti – profesori S. SurRaia)postmenopauzis dros gul-sisxlZarRv-Ta sistemis paTologiebi mniSvnelovanadgils ikavebs qalTa avadobis struqturaSi(1,6). cnobilia, rom estrogenebsaxasaiTebs dacviTi moqmedeba gulsa dasisxlZarRvebze, amitom, sakvercxeebisfunqciis SewyvetasTan erTad, mkveTradizrdeba gul-sisxlZarRvTa sistemis daavadebaTaricxvi. estrogenebis deficitisfonze vlindeba ekg parametrebis cvlilebamosvenebul mdgomareobaSi (ufroxSirad parkuWovani kompleqsis ST-T cvlileba)(3,4). am darRvevebis aRmosafxvreladmniSvnelovania hormonCanacvlebiTiTerapia (hCT), romelic ganixileba,rogorc gul-sisxlZarRvTa sistemisdaavadebaTa prevenciis strategia (3, 4, 5).kvlevis mizani iyo ekg parametrebiscvlilebebis gamovlena dinamikaSi hormonCanacvlebiTiTerapiis fonze postmenopauzisdros qalebSi.gamokvlevis masala da meTodebi:gamokvleuli iyo 61 qali, romelTa asakiSeadgenda 45-60 wels (saSualo asaki54,15); menopauzis xangrZlivoba iyo 1-10wlamde. ekg gamokvleva tardebodaaparatze – kardiografi _ `Megacart~-iT,hormonCanacvlebiTi Terapiis dawyebamdeda mkurnalobis fonze, yovel 3 TveSierTxel. yvela gamokvleuli dayofiliiyo sam jgufad. pirvel jgufSi gaerTianda23 qali, romlebic Rebulobdnen klimens(germania), meore jgufSi – aseve 23qali, romlebic mkurnalobdnen klimonormiT(germania), xolo mesame jguf-Si – 15 qali (sakontrolo jgufi).gamokvlevis Sedegebi: gamokvlevisdros yuradReba eqceoda Civilebs gulsisxlZarRvTasistemis mxridan, romelicaReniSneboda yvela pacients: sxvadasxvalokalizaciisa da intensivobis tkiviliTgulis areSi, tkivili dakavSirebuli fizikurdatvirTvasTan, stresul situaciasTan,qoSini, moxrCobis SegrZneba, simZimisSegrZneba mkerdis Zvlis ukan, gulisfriali, taqikardia, gulis ritmis darRveva,bradikardia, arteriuli wnevis momateba,simpaTikur-adrenaluri krizebi.yvelaze xSiri Civili iyo taqikardia,romelic gamouvlinda gamokvleulTa82%-s da tkivili gulis areSi (77,1%). taqikardiaaRiniSneboda rogorc fizikuridatvirTvisas, ise RamiT, Zilis dros dastresul situaciaSi. 5(8,2%) avadmyofsanamnezSi aReniSneboda paroqsizmulitaqikardiis Setevebi, romlebic ZnelademorCileboda mkurnalobas.gulis areSi tkivilebi atarebda sxvadasxvaxasiaTs, magram ar iyo dakavSirebulifizikur datvirTvasTan da xSirad aRmocendeboda`wamoxurebis~, `alebis~ dros.rogorc kvlevebi aCvenebs, tkivilebi gulisareSi klimaqteruli sindromis drosar aris dakavSirebuli ekg-is cvlilebebTan,gansxvavebiT gid-iT pacientebisagan (4).sxvadasxva xasiaTis cvlileba ekg-zeaReniSneboda 46 (75,41%) qals, maTgan 24-s,postmenopauzis xangrZlivobiT – 5 weli