Kaks uut potentsiaalset markerit kreatiniini taseme mÃµjutajana

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TÄNUAVALDUSED Sooviksin tänada oma juhendajat, Riin Tamme, suurepärase abi ja toetuse eest. Samuti avaldan tänu kaasjuhendaja Egon Urgardile ning statistilise abi eest tänan Evelin Mihailovi ja Reedik Mägi. Lisaks tänan ka biotehnoloogia õppetooli kollektiivi. Suured tänusõnad lähevad toetuse eest ka sõpradele, lähedastele ja perekonnale. 28
KASUTATUD KIRJANDUS Ahn, W. S., Bae, S. M., Lee, J. M., Namkoong, S. E., Han, S. J., Cho, Y. L., jt. (2004). Searching for pathogenic gene functions to cervical cancer. Gynecol Oncol. 93: 41-48. Arnould-Taylor, W. E. 1998. The Genito-Urinary system, p. 76-77. In A textbook of anatomy and physiology, 3 rd ed. Stanley Thornes, Cheltenham. Badenas, C., Praga, M., Tazón, B., Heidet, L., Arrondel, C., Armengol, A., jt. (2002). Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria. J Am Soc Nephrol. 13: 1248-1254. Ceriotti, F., Boyd, J. C., Klein, G., Henny, J., Queraltó, J., Kairisto, V., Panteghini, M. (2008). Reference intervals for serum creatinine concentrations: assessment of available data for global application. Clin Chem. 3: 559-566. Chambers, J. C., Zhang, W., Lord, G. M., van der Harst, P., Lawlor, D. A., Sehmi, J. S., jt. (2010). Genetic loci influencing kidney function and chronic kidney disease. Nat Genet. 42: 373-375. Chang, Y. S., Ko, T. H., Hsu, T. J. ja Syu, M. J. (2009). Synthesis of an imprinted hybrid organic − inorganic polymeric so l− gel matrix toward the specific binding and isotherm kinetics investigation of creatinine. Anal Chem. 8: 2098-2105. Ciarimboli, G., Lancaster, C. S., Schlatter, E., Franke, R. M., Sprowl, J. A., Pavenstädt, H., jt. (2012). Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients. Clin Cancer Res. 18: 1101-1108. Cockcroft, D. W. ja Gault, M. H. (1976). Prediction of creatinine clearance from serum creatinine. Nephron. 16: 31-41. Cohen, M. (2008). What is the normal serum creatinine concentration in children? Ped.Radiol. 38: 1265-1265. Coresh, J., Wei, G. L., McQuillan, G., Brancati, F. L., Levey, A. S., Jones, C., jt. (2001). Prevalence of high blood pressure and elevated serum creatinine level in the United States: Findings from the third national health and nutrition examination survey (1988- 1994). Arch Intern Med. 161: 1207. Culleton, B. F., Larson, M. G., Wilson, P. W. F., Evans, J. C., Parfrey, P. S. ja Levy, D. (1999). Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney Int. 56: 2214-2219. Driver, A. G. ja McAlevy, M. T. (1980). Creatinine height index as a function of age. Am J Clin Nutr. 33: 2057-2057. Dombkowski, A. A., Cukovic, D., Novak, R. F. (2006). Secretome analysis of microarray data reveals extracellular events associated with proliferative potential in a cell line model of breast disease. Cancer Lett. 241:49-58. Dyda, F., Klein, D. C. ja Hickman, A. B. (2000). GCN5-related N-acetyltransferases: A structural overview. Annu Rev Biophys Biomol Struct. 29: 81-103. Filipski, K. K., Mathijssen, R. H., Mikkelsen, T. S., Schinkel, A. H. ja Sparreboom, A. (2009). Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity. Clin Pharmacol Ther. 86: 396-402. Fitch, C. D. ja Sinton, D. W. (1964). A study of creatine metabolism in diseases causing muscle wasting. J Clin Invest. 43: 444-452. 29
Page 1 and 2: TARTU ÜLIKOOL LOODUS- JA TEHNOLOOG
Page 3 and 4: 2.2.6. Statistiline analüüs .....
Page 5 and 6: SISSEJUHATUS Kreatiniin on kreatiin
Page 7 and 8: Nefroni ühes otsas on karikakujuli
Page 9 and 10: 1.2.1. Kreatiniini moodustumine ini
Page 11 and 12: olevatest metaboliitidest ja ravimi
Page 13 and 14: väärtuse ning võtavad arvesse in
Page 15 and 16: Kui suudetakse kõrge haigusriskiga
Page 17 and 18: SYT1 geenis olevad markerid asuvad
Page 19 and 20: 1) edukalt genotüpiseeritud marker
Page 21 and 22: potentsiaalset lookust kromosoomide
Page 23 and 24: informatsiooni haiguste kujunemise
Page 25 and 26: tähtis roll SAM-lt saadud metüül
Page 27: Two new potential markers in variat
Page 31 and 32: Jones, J. D. ja Brunett, P. C. (197
Page 33 and 34: Pattaro, C., Aulchenko, Y. S., Isaa

Kaks uut potentsiaalset markerit kreatiniini taseme mÃµjutajana

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