1 Menneskets genom

18209 01.fm7 Page 44 Friday, March 3, 2006 12:37 PM
1 Menneskets genom
44
a. Transkription
5'
3'
DNA-dobbelthelix
b. Translation
RNA
Methionin Glycin Serin Isoleucin Glycin Alanin
Polypeptid
A U G G G C U C C A U C G G C G C A G C A A G C
5' 1 2 3 4 5 6 7 8 3'
Codons
mRNA
c. Translationsforløb
3'
C C G C G T
5' A U G G G C U C C A U G G G C U C C
A G U U A A U C C 3'
U A C
Ribosom
Met
1. Initiering
d. Strukturen af transfer-RNA (tRNA)
1. Kløverbladstruktur
5'
G
C
G
G
A
U
A
C
C
A
C
G
C
U
U
A
A
G A C A C C U
U
G A
U
G
C U C A
C U G U G C
G G A G C U
G G
A
A
G
C
C
A
G
A
C
U
G A A
Loop 3
Loop 1
Variabel loop
G
G
U
C
Loop 2 A
3'
Anticodon
Figur 1.29 Se Billedtekst på siden overfor.
Met
C C G
Gly
Ribosom
A G G
Ser
2. Elongering
Phe
2. Tredimensionel struktur
Loop 3
20
Variabel loop
Anticodon-loop
(Loop 2)
54
44
32
U C A
Leu Met Ser
64
Ribosom
3. Terminering
4
7
26
38
12
69
5'
Loop 1
Anticodon
72
3'
5'
76
3'
Acceptorende