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96 D. G. Mayo and D. R. Cox<br />

to make the correction. In short, it would be very unwise to dismiss the possibility<br />

of learning from data something new in a totally unanticipated direction, but one<br />

must discriminate the contexts in order to gain guidance for what further analysis,<br />

if any, might be required.<br />

5. Concluding remarks<br />

We have argued that error probabilities in frequentist tests may be used to evaluate<br />

the reliability or capacity with which the test discriminates whether or not the<br />

actual process giving rise to data is in accordance with that described in H0. Knowledge<br />

of this probative capacity allows determination of whether there is strong evidence<br />

against H0 based on the frequentist principle we set out FEV. What makes<br />

the kind of hypothetical reasoning relevant to the case at hand is not the long-run<br />

low error rates associated with using the tool (or test) in this manner; it is rather<br />

what those error rates reveal about the data generating source or phenomenon. We<br />

have not attempted to address the relation between the frequentist and Bayesian<br />

analyses of what may appear to be very similar issues. A fundamental tenet of the<br />

conception of inductive learning most at home with the frequentist philosophy is<br />

that inductive inference requires building up incisive arguments and inferences by<br />

putting together several different piece-meal results; we have set out considerations<br />

to guide these pieces. Although the complexity of the issues makes it more difficult<br />

to set out neatly, as, for example, one could by imagining that a single algorithm<br />

encompasses the whole of inductive inference, the payoff is an account that approaches<br />

the kind of arguments that scientists build up in order to obtain reliable<br />

knowledge and understanding of a field.<br />

References<br />

[1] Birnbaum, A. (1977). The Neyman–Pearson theory as decision theory, and as<br />

inference theory; with a criticism of the Lindley–Savage argument for Bayesian<br />

theory. Synthese 36, 19–49.<br />

[2] Carnap, R. (1962). Logical Foundations of Probability. University of Chicago<br />

Press.<br />

[3] Cochran, W. G. (1965). The planning of observational studies in human<br />

populations (with discussion). J.R.Statist. Soc. A 128, 234–265.<br />

[4] Cox, D. R. (1958). Some problems connected with statistical inference. Ann.<br />

Math. Statist. 29, 357–372.<br />

[5] Cox, D. R. (1977). The role of significance tests (with discussion). Scand. J.<br />

Statist. 4, 49–70.<br />

[6] Cox, D. R. and Hinkley, D. V. (1974). Theoretical Statistics. Chapman<br />

and Hall, London.<br />

[7] Cox, D. R. and Snell, E. J. (1974). The choice of variables in observational<br />

studies. J. R. Statist. Soc. C 23, 51–59.<br />

[8] De Finetti, B. (1974). Theory of Probability, 2 vols. English translation from<br />

Italian. Wiley, New York.<br />

[9] Fisher, R. A. (1935a). Design of Experiments. Oliver and Boyd, Edinburgh.<br />

[10] Fisher, R. A. (1935b). The logic of inductive inference. J. R. Statist. Soc.<br />

98, 39–54.<br />

[11] Gibbons, J. D. and Pratt, J. W. (1975). P-values: Interpretation and<br />

methodology. American Statistician 29, 20–25.

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