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GMO Myths and Truths

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3.9 Myth: Genetic engineering will deliver more nutritious crops<br />

Truth: No GM crop that is more nutritious than its non-GM<br />

counterpart has been commercialised <strong>and</strong> some <strong>GMO</strong>s are less<br />

nutritious<br />

GM proponents have long claimed that genetic<br />

engineering will deliver healthier <strong>and</strong> more<br />

nutritious “biofortified” crops. However, no such<br />

nutritionally enhanced GM foods are available in<br />

the marketplace. In some cases, GM foods have<br />

been found to be less nutritious than their non-<br />

GM counterparts, due to unexpected effects of the<br />

genetic engineering process.<br />

Examples include:<br />

● GM soy had 12–14% lower levels of cancerfighting<br />

isoflavones than non-GM soy. 119<br />

● Canola (oilseed rape) engineered to contain<br />

vitamin A in its oil had much reduced vitamin<br />

E <strong>and</strong> an altered oil-fat composition, compared<br />

with the non-GM control. 120<br />

● Experimental GM rice varieties had unintended<br />

major nutritional disturbances compared with<br />

non-GM counterparts, although they were<br />

grown side-by-side in the same conditions.<br />

The structure <strong>and</strong> texture of the GM rice grain<br />

was affected <strong>and</strong> its nutritional content <strong>and</strong><br />

value were dramatically altered. The variation<br />

ranged from 20 to 74% for amino acids, from<br />

19 to 38% for fatty acids, from 25 to 57% for<br />

vitamins, from 20 to 50% for nutritionally<br />

important trace elements, <strong>and</strong> 25% for protein.<br />

GM rice varieties variously showed markedly<br />

decreased levels of vitamin E, protein, <strong>and</strong><br />

amino acids. The authors said that their<br />

findings “provided alarming information with<br />

regard to the nutritional value of transgenic<br />

rice” <strong>and</strong> showed that the GM rice was not<br />

substantially equivalent to non-GM. 121<br />

3.9.1. Golden Rice: More hype than<br />

hope?<br />

The best-known attempt to nutritionally improve<br />

a GM crop is beta-carotene-enriched “Golden<br />

Rice”. 122,123 The crop is intended for use in poor<br />

countries in the Global South, where vitamin A<br />

deficiency causes blindness, illness, <strong>and</strong> deaths.<br />

However, despite over a decade’s worth of<br />

headlines hyping Golden Rice as a miracle crop, it<br />

is still not available in the marketplace.<br />

GM proponents blame excessive regulation<br />

<strong>and</strong> anti-GM activists for delaying the<br />

commercialisation of Golden Rice. But the real<br />

reasons for the delay seem to be basic research<br />

<strong>and</strong> development problems. The first Golden Rice<br />

variety had insufficient beta-carotene content <strong>and</strong><br />

would have needed to be consumed in kilogram<br />

quantities per day to provide the required daily<br />

vitamin A intake. 122 As a result, a totally new GM<br />

rice variety had to be generated with much higher<br />

beta-carotene content. 123<br />

Also, the process of backcrossing Golden Rice<br />

with varieties that perform well in farmers’ fields<br />

in order to ensure a viable product has taken many<br />

years. 124,125 A 2008 article in the journal Science<br />

said that there was still a “long way to go” in the<br />

backcrossing process. 124<br />

It has taken over a decade to develop Golden<br />

Rice. Yet as of 2012, field trials have not been<br />

completed to ensure that it grows successfully<br />

in local conditions. Nor has it been tested in<br />

toxicological feeding trials on animals to establish<br />

whether it is safe to eat. Nevertheless, the rice<br />

was fed to human subjects (adults <strong>and</strong> children)<br />

in experiments conducted by researchers at<br />

Tufts University, Boston, MA. This was not a<br />

safety study but an efficacy test to see whether<br />

the human subjects assimilated sufficient<br />

beta-carotene <strong>and</strong> converted it to vitamin A.<br />

The efficacy test was conducted without basic<br />

toxicological testing having been carried out.<br />

This was condemned as a breach of medical ethics<br />

<strong>and</strong> the Nuremberg Code (established after<br />

World War II to prevent a repeat of inhumane<br />

Nazi experiments on humans) by a group of<br />

international scientists in a letter of protest to the<br />

Tufts researchers. 126<br />

In contrast with the problematical Golden Rice,<br />

inexpensive <strong>and</strong> effective methods of combating<br />

<strong>GMO</strong> <strong>Myths</strong> <strong>and</strong> <strong>Truths</strong> 57

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