2006 ที่น้องแอนทำ.pmd - Mahidol University

Mahidol University Abstract of International Publications 2006
No.113
Author(s) : Buranakitjaroen P.
Title : An audit of blood pressure control in clinical practice in Thailand.
Source : Journal of the Medical Association of Thailand. 89 (Suppl.5): S8 – S17, 2006 (Nov).
Document Type : Article.
Keywords : Audit, Hypertension.
Abstract : To gain “real life” data on the BP control of hypertensive patients in clinical practice
in Thailand, a multi – centre cross – sectional study was carried out. Demographic
data, cardiovascular risk factors, and antihypertensive regimens were collected. A
total of 1,259 patients were enrolled between October 2003 and December 2003, 924
cases from 6 regions of different levels of health care and 335 cases from 4 medical
training centres and a tertiary care hospital in Bangkok. Eighty one percent of the
patients, age ranged from 45 to 75 years (61.2 11.6). Forty four percent of patients in
audit had a BP < 140/90 mm Hg and only 12.3% of DM patients had attained a JNC 7
recommended BP target of 130/80 mm Hg. Hypercholesterolaemia (65.3%) was the
most prevalent risk followed by DM (27.7%). Antihypertensive drug used at the initial
visit compared with the last visit were ARB (0.9% vs 6.1%), ACE Inhibitors (30.1% vs
40.0%), – blockers (27.3% vs 46.7%), CCBs (23.2% vs 37.7%), and diuretics (46.0% vs
53.5%). In addition, the numbers of antihypertensive drugs used at the initial visit
compared with the last clinic visit were one drug (62.0% vs 33.0%), two drugs (29.7%
vs 45.8%), three drugs or more (3.7% vs 20.4%), with an average of 1.3 0.6 vs 1.9 0.8
drugs per patient. Two thirds of patients (66.2%) were on 2 or more antihypertensive
drugs. Among the type 2 DM, 5% had records of microalbuminuria, and 50.6% and
9.8% were receiving ACE Inhibitors and ARBs, respectively at the last clinic visit.
No.114
Author(s) : Buranakitjaroen P, Phoojaroenchanachai M, Saravich S.
Title : Hypertension study among attendants at the board of investment fair 2000.
Source : Journal of the Medical Association of Thailand. 89 (Suppl.5): S18 – S27, 2006 (Nov).
Document Type : Article.
Keywords : Board of investment fair, Hypertension, Prevalence.
Abstract : To study the prevalence of hypertension, blood pressure (BP) controlled and
cardiovascular risk factors in people who attended the Board of Investment 2002 Fair
(BOI Fair). Altogether 1,774 participants aged more than 15 years old voluntarily
participated in BP check – ups during the 3rd – 17 th February 2000 at the BOI Fair.
Three hundred and fifty participants (19.7%) were known cases of hypertension (HT)
and 340 participants (19.2%) were newly diagnosed hypertension cases (NHT). Of the
HT group, 216 cases were under current treatment (61.7%) and only 69 cases (31.9%)
had adequate BP control. Of the NHT group, cardiovascular risk factors were found
more frequently than in normotensive participants. This study indicates the necessity
of building up awareness in the population, improving in clinical detection, effectively
controlling of the risk factors and the normalization of BP. This might prevent
hypertension and reduce the cardiovascular disease.
No.115
Author(s) : Buranakitjaroen P, Phoojaroenchanachai M, Saravich S.
Title : Prevalence of erectile dysfunction among treated hypertensive males.
Source : Journal of the Medical Association of Thailand. 89 (Suppl.5): S28 – S36, 2006 (Nov).
Document Type : Article.
Keywords : Erectile dysfunction, Hypertension.
Abstract : Objective: Study the prevalence rate of erectile dysfunction (ED) in treated
hypertensive males. Material and Method: Four hundred and twenty nine patients
attending the outpatient clinic at Siriraj Hospital between April 2001 and October
2002 were interviewed. The International Index of Erectile Function, a 5 – item
version (IIEF – 5) questionnaire was used. All questions were carried out by a well –
trained interviewer. Result: Of the 429 patients (mean age of 57.5 12.0 years)
interviewed, 241 cases (56.2%) reported ED. The prevalence was found to increase
with age: from 0% in men aged < 40 years, 47.4% in men aged 40 – 59 years, and 75.3%
in men aged e•60 years. Risk of ED was significantly (p < 0.01) associated with the
elderly (OR=4.7, 95%CI = 3.1 – 7.1), patients who suffered from hypertension longer
than 5 years (OR = 4.0, 95%CI = 2.6 – 6.1), those with a history of back/pelvic surgery
(OR = 2.8, 95%CI = 1.4 – 4.8), smoking (OR = 1.5, 95%CI = 1.0 – 2.2), alcohol ingestion
(OR = 2.0, 95%CI = 1.3 – 3.0), diabetes mellitus (OR = 6.3, 95%CI = 3.5 – 11.2),
diuretics (OR = 1.9, 95%CI = 1.3 – 2.8), and alpha – 2 agonist (OR = 7.9, 95%CI = 2.3
– 26.1) usage. On multivariate regression analyses, the elderly (OR = 4.0, 95%CI = 2.5
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