2006 ที่น้องแอนทำ.pmd - Mahidol University

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Mahidol University Abstract of International Publications 2006 No.141 Author(s) : Chaiyakunapruk N, Laowakul A, Karnchanarat S, Pikulthong N, Ongphiphadhanakul B. Title : Community pharmacy – based implementation and evaluation of an Osteoporosis Self – Assessment Tool for Asians. Source : Journal of the American Pharmacists Association. 46 (3): 391 – 396, 2006. Document Type : Article. Keywords : Community and ambulatory pharmacy, Health screenings, Osteoporosis, Osteoporosis Self – Assessment Tool for Asians, Physicians, Public health, Risk assessment, Thailand. Abstract : Objectives: To implement an osteoporosis screening and referral program in community pharmacies and evaluate the use of the Osteoporosis Self – Assessment Tool for Asians (OSTA) as the screening instrument. Design: Uncontrolled study. Setting: Three community pharmacies in Bangkok, Thailand. Patients: 51 women aged 50 years or older without prior diagnosis of osteoporosis; three community pharmacists; six hospital – based physicians. Intervention: OSTA assessment by community pharmacists of the risks of osteoporosis in patients; counseling of patients about diet and exercise; referral of patients at high risk (OSTA index value less than – 4) to hospitals where pharmacists had made arrangements in advance; and assessment of satisfaction and opinions of participating patients and physicians. Results: Of the 51 patients, 32 (62.7%) were categorized as low risk (OSTA index value > – 1) and 19 (37.3%) as intermediate risk (OSTA index value range, – 4 to – 1). The majority of patients (97%) were satisfied with the program and the knowledge gained. Even though no high – risk patients were identified and referred for medical care, all six participating physicians agreed with having risk assessment service in community pharmacies and the prearranged referral system, and five of six physicians believed that OSTA results were valuable in the management of osteoporosis. Conclusion: Community pharmacy – based osteoporosis risk assessment services using OSTA were well accepted by the patients and participating physicians. Public health benefits may result from the provision of osteoporosis risk screening services in community pharmacies in Thailand and other Asian countries. No.142 Author(s) : Chaiyaroj S, Viengteeravat S, Bhumarangura W, Khajarern S, Leelayana P, Purintrapiban B. Title : Techniques and results of off – pump coronary artery bypass grafting using homemade intracoronary shunt. Source : Journal of the Medical Association of Thailand. 89 (9): 1434 – 1439, 2006. Document Type : Article. Keywords : Off – pump CABG, Ramathibodi intracoronary shunt. Abstract : Background: The outcome of the off – pump coronary artery bypass grafting (CABG) is highly dependent on surgical techniques. To overcome problems of intraoperative hemodynamic instability and avoid potential injury to coronary artery arising from occlusive technique, the authors have modified the strategy of performing distal anastomosis by using the authors’ homemade intracoronary artery shunt. Objective: To document the results of off – pump CABG using the authors’ homemade intracoronary shunt. The characteristics of shunt and techniques are demonstrated. Material and Method: The shunt is constructed from silicone tubing (Allied Biomedical Company, Paso Robles, CA). It has been successfully used for distal anastomoses in off – pump coronary artery bypass surgery. All 170 consecutive patients who had off – pump CABG from October 2002 to May 2005 were evaluated. Data were collected retrospectively. Average grafts per patient were 3.5. Arterial grafts were used in most cases (90%). Conversion rate was 2.8%. Patients were followed up at 3 weeks, 6 weeks, and bimonthly thereafter. Results: In a 23 – month follow – up, the operative mortality rate was 0.5% (one patient). Complications included stroke in 3 patients (1.8%) and post – operative AF in 12 patients (7.12%). Of 170 patients, 12 patients (7.05%) required intraoperative or postoperative intraaortic balloon pump support. The early results were good and satisfactory. Conclusion: Off – pump CABG can be successfully performed using the authors’ homemade intracoronary artery shunt with better hemodynamic control. The techniques are safe, simple, reliable, and effective. 50
Mahidol University Abstract of International Publications 2006 No.143 Author(s) : Chaiyut N, Amornsakchai T, Kaji H, Horii F. Title : Solid – state C – 13 NMR investigation of the structure and dynamics of highly drawn polyethylene – detection of the oriented non – crystalline component. Source : Polymer. 47 (7): 2470 – 2480, 2006 (Mar). Document Type : Article. Keywords : Drawn polyethylene, Solid – state C – 13 NMR, Oriented non – crystalline. Abstract : The structure and dynamics of highly drawn polyethylene samples were studied by solid – state C – 13 NMR spectroscopy. The analyses of the C – 13 spin – lattice relaxation time (T – 1C) and the C – 13 spin – spin relaxation time (T – 2C) have revealed that at least three components with different Tic and T – 2C values, which correspond to the crystalline, less mobile non – crystalline, and rubbery amorphous components, exist for these materials, as in the case of isothermally crystallized samples. However, another component with a mass fraction of 0.13 – 0.18 exists which has a C – 13 chemical shift very close to that of the orthorhombic crystalline phase but has an extremely small T – 1C. Since this component is believed to have the all – trans conformation, it is termed fast all – trans. The chemical shift anisotropy (CSA) spectra for various samples that have small T – 1C values have been recorded and resolved into those of the non – crystalline and fast all – trans components. As expected, the CSA spectra of the less mobile non – crystalline and rubbery amorphous components that have the smallest T – 1C values display only a slight asymmetry. In contrast, the CSA spectrum of the fast all – trans component displays higher asymmetry. However, the spectrum is still much narrower than that of the normal orthorhombic crystalline phase, indicating a high degree of motional averaging. It is proposed that this component should be a highly oriented non – crystalline component, which may exist as taut tie – molecules traversing the non – crystalline region. To account for the narrow CSA, this component must undergo rapid fluctuation with large amplitudes at the torsional potential minimum in each C – C bond and possibly an additional random jump or diffusional rotation around the chain axis. Additional measurements obtained by aligning the draw axis of the sample parallel or perpendicular to the static magnetic field indicate that the fast all – trans component is oriented along the drawing direction and subjected to rapid motion around the chain axis. No.144 Author(s) : Chalermchockcharoenkit A, Sirimai K, Chaisilwattana P. Title : High prevalence of cervical squamous cell abnormalities among HIV – infected women with immunological AIDS – defining illnesses. Source : Journal of Obstetrics and Gynaecology Research. 32 (3): 324 – 329, 2006 (Jun). Document Type : Article. Keywords : Immunological AIDS – defining illness, Squamous cell abnormalities. Abstract : To assess the results of Pap smear at postpartum scheduled visit, especially the prevalence of squamous cell abnormalities including association with CD4(+) T – lymphocyte count (CD4(+) count) levels at delivery among HIV – infected women between the years 1996 and 2004. As part of the research and implementation programs of short course antiretroviral regimens for the prevention of mother to child perinatal HIV transmission in HIV – infected pregnant women delivered at Siriraj hospital, CD4(+) count at delivery and Pap smear at postpartum were evaluated. Among 636 women, 13.3% had squamous cell abnormalities. Seventy – seven cases (90.6%) of squamous cell abnormalities were low grade squamous intraepithelial lesions. The prevalence of squamous epithelial cell abnormalities detected by Pap smear, was higher in women whose CD4(+) count at delivery was < 200 cells/mu L than in women whose CD4(+) count at delivery was >= 200 cells/mu L, with a significant difference (21.2%vs 12.2%). All HIV – infected pregnant women should be evaluated for clinical and immunological status during the antepartum period. Pelvic examination and Pap smear should be considered as a part of this evaluation. They should receive comprehensive health – care services that continue after pregnancy, including postpartum gynecologic examination and Pap smear. Women with normal cervical cytological findings but low CD4(+) count should be offered an antenatal Pap smear and long – term follow – up including a 6 – monthly Pap smear. 51
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2006 ที่น้องแอนทำ.pmd - Mahidol University

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