Contents Chapter Topic Page Neonatology Respiratory Cardiology

3.3.6 Pregnancy (live vaccine theoretical risk to foetus) UNLESS there is
significant exposure to serious conditions like polio or yellow fever in
which case the importance of vaccination may outweigh the possible
risk to the foetus.
3.4 Killed vaccines are generally safe.
The only Absolute contraindications are SEVERE local (induration involving >
2/3 of the limbs) or severe generalised reaction in the previous dose (i.e.
Temp > 39°C, anaphylaxis, persistent screaming, convulsions).
3.5 Specific Contraindications
3 Weeks 3 Months
Live Vaccine HNIG Live Vaccine
3.5.1 BCG - Not to be given to symptomatic HIV infected children.
3.5.2 Hep B vaccine – Severe hypersensitivity to aluminium or thiomersal.
(Not needed for HBsAg or Ab positive)
3.5.3 Pertussis
Progressive neurological diseases like infantile spasm, tuberous
sclerosis.
Severe reaction to previous dose i.e.
a. Anaphylaxis b. Collapse or shock-like states
c. Hyporesponsive states d. Fits and fever within 72 hr
e. Fever > 40.5 C within 48 hours e. Encephalitis within 7 days
f. Severe local reaction involving 2/3 of limbs.
Static neurological diseases, developmental delay, personal or
family history of fits are NOT contraindications.
Severe hypersensitivity to aluminium and thiomersal. And point 3.4
as above
3.5.4 Diphtheria & Tetanus: Severe hypersensitivity to aluminium and
thiomersal. And point 3.4 as above.
3.5.5 Polio
Diarrhoea & vomiting.
Hypersensitivity to penicillin, neomycin, streptomycin or
polymycin.
Within 3 week from a proposed tonsillectomy (remote risk of
vaccine induced bulbar polio).
Polio (IPV) is to be used for immunocompromised children, their
siblings and household contacts. OPV if given to
immunosuppressed or HIV positive children tend to cause
prolonged excretion of the OPV and be hazardous to care givers.