Contents Chapter Topic Page Neonatology Respiratory Cardiology

Medications used in Neonatal Resuscitation:
Type Indications Concentration
to Administer
Adrenaline 1) HR < 60/min
despite a
1:10 000
minimum of 30 (The only
seconds of preparation
adequate available is
ventilation with 1:1000. Dilute
100 % O2 and 1ml of
chest
Adrenaline
compressions. 1:1000 with
2) Heart rate is distilled water
zero.
to 10ml)
Volume
Expanders
Sodium
Bicarb.
Naloxone
HCl
1) Prolonged arrest
not responding to
resuscitation
2)Evidence or
suspicion of acute
blood loss with signs
of hypovolaemia
1)Severe metabolic
acidosis is
suspected or
proven by blood
analysis;
2)Prolonged arrest
not responding to
resuscitation
Severe respiratory
depression and a
history of maternal
narcotics
administered within
the past 4 hours.
Normal Saline
Ringer's lactate
0.5 mEq/ml
(4.2% solution)
0.4 mg/ml
(dilution that is
usually
available)
1.0 mg/ml
Prepara- Dosage/
tion Route
1 ml 0.01-0.03
mg/kg. 0.1-
0.3 ml/kg. IV
or ET
40 ml 10 ml/kg
IV
20 ml or
two 10mlprefilled
syringes
1 ml
2 mEg/Kg
IV only.
(4 ml/kg)
0.1 mg/kg
(0.25 ml/kg)
IV ET IM SC
0.1 mg/kg
(0.1 ml/kg)
IV ET IM SC
Rate/
Precautions
Give rapidly.
May dilute with
normal saline to
1-2 ml if giving
via ET.
Give over 5 – 10
minutes.
Give by syringe
or IV drip.
Give slowly,
over at least 2
minutes.
Give only if
infant is being
effectively
ventilated.
Give rapidly.
IV, ET
preferred. IM,
SC acceptable.