Contents Chapter Topic Page Neonatology Respiratory Cardiology

4.8 Rubella
May have rash, fever, lymphadenopathy, thrombocytopenia, transient
peripheral neuritis.
Arthritis and arthralgia occurs in up to 3% of children and 20% of adults
who receive the vaccine.
Rarely polyneuropathy (like Guillain-Barre syndrome can occur).
4.9 BCG
Local reaction :a papule at site of vaccination occurs within 2 to 6 weeks.
This grows and flattens with scaling and crusting. Occasionally a
discharging ulcer may occur. This heals leaving a BCG scar of at least 4
mm in successful vaccination.
BCG adenitis may occur.
4.10 Influenza and Rabies
Transient swelling, redness, pain and induration locally.
Myalgia, malaise and fever for 1 – 2 days starting within a few hours post
vaccination. Very rarely neurological or anaphylactic reaction occurs.
4.11 Pneumococcal
Local reaction. Fever and myalgia in less than 1% of vaccines. Rarely
neurological disorder (Guillain-Barre), glomerulonephritis, ITP or
anaphylaxis.
4.12 Hepatitis A
Local reaction. Flu-like symptoms lasting 2 days in 10% of vaccines.
4.13 Hepatitis B
Local reaction. Fever and flu-like symptoms in 1 st 48 hours. Rarely
erythema multiforme or urticaria.
4.14 Typhoid (Typhim Vi):
Local reaction. Myalgia, malaise, nausea, headaches and fever in 3% of
recipients.
4.15 Cholera
Local reaction. Headache, fever and malaise for 1 – 2 days. Rarely
anaphylactic reaction, neurological symptoms including cerebral and
meningeal irritation may occur.
Repeated vaccination over a few years can result in hypersensitivity to the
protein components.
4.16 Meningococcus A, C, Y & W-135
Local reaction. Irritability, fever and rigors for 1 – 2 days. Very rarely
anaphylaxis.