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Contents Chapter Topic Page Neonatology Respiratory Cardiology

Contents Chapter Topic Page Neonatology Respiratory Cardiology

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5.5 Close contacts of immuno-deficient children and adults must be immunized,<br />

particularly against measles and polio (use IPV).<br />

5.6 In cases of contact with a patient with invasive Haemophilus influenzae B<br />

disease:<br />

5.6.1 Close contacts in a household, nursery or kindergarden under the age<br />

of 4 years should be immunised.<br />

5.6.2 Rifampicin prophylaxis should be given to all household contacts at 20<br />

mg/kg once daily (Maximum 600 mg) for 4 days (except pregnant<br />

women - one IM dose of ceftriaxone )<br />

5.6.3 Index case should be immunised irrespective of age.<br />

5.7 Asplenia (Elective or emergency splenectomy; asplenic syndromes; sickle cell<br />

anaemia) – susceptible to encapsulated bacteria and malaria.<br />

5.7.1 Pneumococcal, Meningococcal A, C, Y & W-135 and Haemophilus<br />

influenza b vaccines should be given.<br />

5.7.2 For elective splenectomy (and also chemotherapy or radiotherapy); it is<br />

preferable to give the vaccines 2 or more weeks before the procedure.<br />

However they can be given even after the procedure.<br />

5.7.3 Penicillin prophylaxis should continue even after vaccination. Ideally for<br />

life. If not until 16 years old for children or 5 years post splenectomy in<br />

adults.<br />

5.8 Babies born to mothers who are HbeAg OR HbsAg positive should be given<br />

Hepatitis B immunoglobulin (200 IU) and vaccinated with the Hepatitis B<br />

vaccine at within 12 hours and not later than 48 hours. Given in different<br />

syringes and at different sites.

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