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Contents Chapter Topic Page Neonatology Respiratory Cardiology

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3.5.6 Rubella - Contraindicated in pregnancy (even though no reported cases<br />

of congenital rubella syndrome due to vaccine).<br />

3.5.7 Measles - If < 9 months old presence of maternal Ab may decrease<br />

immunogenecity. Avoid in persons hypersensitive to neomycin,<br />

polymyxin OR anaphylaxis to egg ingestion.<br />

3.5.8 MMR and Influenza – severe reaction to hen’s eggs or neomycin.<br />

3.5.9 Pneumococcal – children less than 2 years old; revaccination within 3<br />

years has high risk of adverse reaction; avoid during chemotherapy or<br />

radiotherapy and less than 10 days prior to commencement of such<br />

therapy – antibody response is poor. Pregnancy.<br />

3.5.10 Hepatitis A: Severe hypersentivity to aluminium hydroxide,<br />

phenoxyethanol or neomycin.<br />

3.5.11 Typhoid (whole-cell) and Cholera: patients with chronic illness such as<br />

multiple sclerosis, rheumatoid arthritis, diabetes and compensated<br />

cardiac conditions may suffer a relapse.<br />

3.5.12 Meningococcus A, C, Y & W-135: polysaccharide vaccine : Not useful<br />

in children < 2 years old.<br />

3.5.13 Japanese B: contraindicated in immunodeficiency and malignancy,<br />

diabetes, acute exacerbation of cardiac, hepatic and renal conditions.<br />

3.6 The following are NOT contraindications to vaccination in<br />

Children<br />

3.6.1 Mild illness without fever e.g. mild diarrhoea, cough, running nose.<br />

3.6.2 Asthma, eczema, hay fever, impetigo, heat rash, etc.(avoid injection in<br />

area of skin lesion).<br />

3.6.3 Treatment with antibiotics or locally acting steroids.<br />

3.6.4 Child's mother is pregnant.<br />

3.6.5 Breast fed child (does not affect polio uptake).<br />

3.6.6 Neonatal jaundice.<br />

3.6.7 Underweight or malnourished.<br />

3.6.8 Over the recommended age.<br />

3.6.9 Past history of pertussis, measles or rubella (unless confirmed<br />

medically).<br />

3.6.10 Non progressive, stable neurological conditions like Cerebral palsy,<br />

Down’s syndrome, simple febrile convulsions, controlled epilepsy.<br />

mental retardation.<br />

3.6.11 Family history of convulsions.<br />

3.6.12 History of heart disease, acquired or congenital.<br />

3.6.13 Prematurity (give immunisation according to schedule irrespective of<br />

gestational age).

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