Repeated-dose 90-day Oral Toxicity Studies on Whole ... - Europabio

3. Summary statistics and
raw analysis outputs
• EuropaBio Members’ understanding is that EFSA wishes to see
results presented both in terms of means and p-values, and
differences and 95% confidence intervals.
• However, some requirements are less clear, and others (e.g., the
median) seem to be of questionable value in most cases.
• It is the opinion of EuropaBio Members that the following
summary statistics would generally be appropriate:
– Mean, min, max and SD for each treatment group.
– P-values for all fixed effects and specific contrasts.
– Point estimate of the difference between GM and non-GM together with
95% confidence interval for the difference.
• EuropaBio Members seek confirmation from EFSA as to whether
the above list is acceptable.
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