Meiosis, Germ Cells, and Fertilization
Meiosis, Germ Cells, and Fertilization
Meiosis, Germ Cells, and Fertilization
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Homolog Pairing Culminates in the<br />
Formation of a Synaptonemal Complex<br />
• The axial cores are about 400 nm apart<br />
• Programmed double-str<strong>and</strong> DNA breaks<br />
• Recombination complex assembles on a double-str<strong>and</strong> break<br />
• Presynaptic alignment of the homologs<br />
• During synapsis, the transverse filaments link the axial cores of a homolog<br />
pair as a synaptonemal complex, that bridges the gap of only 100 nm.
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