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Meiosis, Germ Cells, and Fertilization

Meiosis, Germ Cells, and Fertilization

Meiosis, Germ Cells, and Fertilization

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Capacitation<br />

• sperm arrive in the oviduct.<br />

• takes about 5–6 hours in humans<br />

• changes in glycoproteins, lipids, <strong>and</strong> ion channels<br />

• change in the resting potential of this membrane<br />

• increase in cytosolic pH<br />

• tyrosine phosphorylation<br />

• unmasking of cell-surface receptors<br />

• greatly increases the motility of the flagellum<br />

• capable of undergoing the acrosome reaction.

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