Meiosis, Germ Cells, and Fertilization

• Sry normally acts by inducing the
expression of Sox9.
• The Sox9 protein directly activates the
gene encoding anti-Müllerian hormone.
• In the absence of either Sry or Sox9, the
genital ridge of an XY embryo develops
into an ovary instead of a testis.
• The supporting cells become follicle cells
instead of Sertoli cells.
• Other somatic cells become theca cells
(instead of Leydig cells),
• PGCs develop along a pathway that
produces eggs rather than sperm.