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European Society of Mycobacteriology - Instituto Nacional de Saúde ...

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PP-115<br />

Nosocomial TB in a laboratory setting<br />

Jaime M S Nina 1,2,3<br />

1 - <strong>Instituto</strong> <strong>Nacional</strong> <strong>de</strong> Saú<strong>de</strong> Doutor Ricardo Jorge<br />

2 - Universida<strong>de</strong> Nova <strong>de</strong> Lisboa<br />

3 - Hospital Egas Moniz<br />

Abstract<br />

TB is recognized as a major cause <strong>of</strong> morbidity and mortality worldwi<strong>de</strong>. Its easily transmissibility is also generally recognized,<br />

both at the family level, in the household, at the place <strong>of</strong> work and insi<strong>de</strong> health care facilities. This last way <strong>of</strong><br />

transmission, properly called nosocomial transmission, has been suspected for long time, and was formally <strong>de</strong>monstrated<br />

in the ward, both among patients, and health care workers. Several pr<strong>of</strong>essional bodies and other institutions, both at<br />

the national and international level, produced gui<strong>de</strong>lines trying to minimize TB transmission to health care workers insi<strong>de</strong><br />

wards and emergency services. Furthermore several countries produced legislation to protect health care workers<br />

against nosocomial TB, and/or inclu<strong>de</strong>d TB in the list <strong>of</strong> pr<strong>of</strong>essional diseases or hazards to health care workers.<br />

However, much less attention has been given to the TB transmission potential to laboratory workers. Even if several<br />

countries moved laboratory work with live TB samples to LSB-3 facilities, the evi<strong>de</strong>nce on which to base this <strong>de</strong>cision is<br />

thin, and no systematic study has been published.<br />

Herein are presented three cases <strong>of</strong> nosocomial transmission insi<strong>de</strong> laboratory settings, in Lisbon. These cases cover all<br />

spectra <strong>of</strong> pr<strong>of</strong>essional differentiation, from basic level auxiliary personnel, to a laboratory technician, and to a microbiologist<br />

physician. In one case the way <strong>of</strong> transmission was a very common kind <strong>of</strong> laboratory acci<strong>de</strong>nt, in another a<br />

common inattention, and in the last one no specific way <strong>of</strong> transmission was found. One <strong>of</strong> the cases was found to be a<br />

MDX TB.<br />

In conclusion, the trend to carry out all routine work with live TB samples only insi<strong>de</strong> a BSL-3 facility seems a right one,<br />

and so it is fully justified. Also justified would be the inclusion <strong>of</strong> health laboratory workers in the legislation that provi<strong>de</strong><br />

safety measures and insurance cover to health care workers.<br />

<strong>European</strong> <strong>Society</strong> <strong>of</strong> <strong>Mycobacteriology</strong> | 30 th Annual Congress | July 2009 | Porto - Portugal<br />

187

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