RPS Conference 2010, Abstracts 2010 - Royal Pharmaceutical Society

BactiFlow ALS ®
(24hr)
AKuScreen ® (24hr) BacT/ALERT ®
(24hr)
Concordance:
Traditional vs RMM 78% 85% 62% 92%
BacT/ALERT ®
(3days)
The results of a guideline cost analysis for the traditional method and the rapid methods of
BactiFlow ALS ® , BacT/ALERT ® and AKuScreen ® are £75, £94, £96 and £100 respectively on a
test batch of TPN (as at time of study).
Conclusion. All RMM systems were able to provide results within 24hrs except BacT/ALERT ®
which was within 3 days. The BacT/ALERT ® system was technically the easiest to use and with
highest condordance when results were read after 3 days, however concordance levels were
the lowest when the system was used within 1 day and compared to the other systems which
detect within 1 day. The recovery results from spiked methotrexate samples indicate low levels
of detection by the RMM systems. The results of this study demonstrate that RMM has the
potential to improve QA of selected NHS manufactured aseptic products.
References
1. British Pharmacopoeia. Appendix XVI C: Efficacy of Antimicrobial Preservation. 2009. HMSO:
London.
2. Aseptic Dispensing for NHS Patients. Farwell report. 1995. Dept of Health
Acknowledgements. Cardiff and Vale University Health Board Small Grant Scheme and
technical support from the three companies involved.