NCCR Guide 2013 - Schweizerischer Nationalfonds (SNF)
NCCR Guide 2013 - Schweizerischer Nationalfonds (SNF)
NCCR Guide 2013 - Schweizerischer Nationalfonds (SNF)
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Topics<br />
Today, knowledge about<br />
biological processes is<br />
obtained from functional<br />
experiments on a limited<br />
number of biochemical<br />
systems, and from a rapidly<br />
increasing amount of<br />
DNA sequence information,<br />
generated in several<br />
genome projects. To bridge<br />
the widening gap between<br />
rapidly increasing information<br />
on genome sequences<br />
and limited know ledge<br />
on the function of gene<br />
products, a quantitative<br />
understanding of the 3Dstructure<br />
of proteins, their<br />
Heads of Individual Research Projects and Associated Groups<br />
Allain Frédéric, Prof.<br />
Ban Nenad, Prof.<br />
Dutzler Raimund, Prof.<br />
Glockshuber Rudolf, Prof.<br />
Grütter Markus, Prof.<br />
Locher Kaspar, Prof.<br />
Medalia Ohad, Prof.<br />
Plückthun Andreas, Prof.<br />
Richmond Timothy J., Prof.<br />
Schuler Ben, Prof.<br />
Schertler Gebhard, Prof.<br />
Stahlberg Henning, Prof.<br />
van Gunsteren Wilfred F., Prof.<br />
Weber-Ban Erika<br />
Wüthrich Kurt, Prof.<br />
folding, and their interactions<br />
with other molecules<br />
is required. Such<br />
understanding is the key<br />
to develop innovative medi<br />
cines, such as new antibiotics<br />
and vaccines, as<br />
well as drugs against<br />
cancer and diseases of<br />
the central nervous, immune,<br />
and cardiovascular<br />
systems. In this <strong>NCCR</strong><br />
specialists in experimental<br />
struc tu re determination<br />
by X-ray crystallography,<br />
NMR spectroscopy<br />
and electron microscopy<br />
/ crystallo gra phy, in protein<br />
biophysical chemistry,<br />
modern molecular biology,<br />
and computational biology<br />
will meet the challenge to<br />
link the ever increasing biological<br />
data generated in the<br />
genomics field with related<br />
structural and functional<br />
information. This <strong>NCCR</strong> is<br />
currently in its third and<br />
final funding period until<br />
<strong>2013</strong>. The major assets resulting<br />
from this project<br />
will be secured longterm<br />
through the foundation of a<br />
center of structural biology<br />
head-quartered in Zürich.<br />
Institut für Molekularbiologie und Biophysik, ETH Zürich<br />
Institut für Molekularbiologie und Biophysik, ETH Zürich<br />
Institut für Biochemie, Universität Zürich<br />
Institut für Molekularbiologie und Biophysik, ETH Zürich<br />
Institut für Biochemie, Universität Zürich<br />
Institut für Molekularbiologie und Biophysik, ETH Zürich<br />
Institut für Biochemie, Universität Zürich<br />
Institut für Biochemie, Universität Zürich<br />
Institut für Molekularbiologie und Biophysik, ETH Zürich<br />
Institut für Biochemie, Universität Zürich<br />
Paul Scherrer Institut, Villigen PSI<br />
C-CINA, Biozentrum, Universität Basel<br />
Laboratorium für physikalische Chemie, ETH Zürich<br />
Institut für Molekularbiologie und Biophysik, ETH Zürich<br />
Institut für Molekularbiologie und Biophysik, ETH Zürich<br />
Third Party Cooperation<br />
Programmes<br />
• EDICT (FP7)<br />
• P-CUBE (FP7)<br />
Research Institutions<br />
• Biochemistry, Brandeis University,<br />
Waltham, US<br />
• Biozentrum, University of Basel,<br />
Basel, CH<br />
• Cancer Research (CSHL), Cold<br />
Spring Harbour Laboratories, US<br />
• Center for Cellular Imaging<br />
and Nanoanalytics,<br />
University of Basel, CH<br />
• Centre de Regulacio Genomica,<br />
Institució Catalana de Recerca i<br />
Estudis Avançats, Barcelona, ES<br />
• Department Biophysical<br />
Chemistry, Max-Planck-Institute<br />
for Intelligent Systems,<br />
Stuttgart, DE<br />
• Département de Microbiologie<br />
et d’Infectiologie,<br />
Université de Sherbrooke, CA<br />
• Department of Biochemistry,<br />
New York University School of<br />
Medicine, New York, US<br />
• Department of Biochemistry,<br />
University of Washington,<br />
Seattle, US<br />
• Department of Biological Sciences,<br />
University of Illinois, Chicago, US<br />
• Department of Biology,<br />
University of Science and<br />
Technology of China, Hefei, CN<br />
• Department of Biophysical<br />
Structural Chemistry, Leiden<br />
Institute of Chemistry, NL<br />
• Department of Chemistry and<br />
Molecular Biology, University of<br />
Gothenburg, Gothenburg, Sweden<br />
• Department of Chemistry,<br />
Ludwig-Maximilian-University<br />
Munich, DE<br />
• Department of Chemistry,<br />
University of Cambridge, GB<br />
• Department of Chemistry, Wayne<br />
State University, Detroit, US<br />
• Department of Genetics, The<br />
Hebrew University of Jerusalem,<br />
Jerusalem, IL<br />
• Department of Hematology, The<br />
Hebrew University of Jerusalem -<br />
Hadassah Medical Organization,<br />
Jerusalem, IL<br />
• Department of Molecular<br />
Biology and Biotechnology,<br />
University of Sheffield, GB<br />
• Department of Molecular Cell<br />
Biology, Weizmann Institute of<br />
Science, Rehovot, IL<br />
• Department of Molecular<br />
Biophysics and Biochemistry,<br />
Yale University, New Haven, US<br />
• Department of Molecular<br />
Medicine, Max Planck Institute of<br />
Biochemistry, Martinsried, DE<br />
• Department of Pharmacology,<br />
School of Medicine, Cleveland, US<br />
• Department of Physics, University<br />
of California, Santa Barbara, US<br />
• Department of Pharmacology,<br />
University of North Carolina,<br />
Chapel Hill, US<br />
<strong>Guide</strong> <strong>2013</strong> | 17