NCCR Guide 2013 - Schweizerischer Nationalfonds (SNF)
NCCR Guide 2013 - Schweizerischer Nationalfonds (SNF)
NCCR Guide 2013 - Schweizerischer Nationalfonds (SNF)
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From transport physiology<br />
to identification<br />
of therapeutic target<br />
<strong>NCCR</strong> TransCure<br />
Home Institution<br />
University of Bern<br />
Start of the <strong>NCCR</strong><br />
November 1, 2010<br />
Research<br />
Projects:<br />
Transporters as targets for<br />
cancer therapy (part A)<br />
Glutamate transporters as<br />
therapeutic targets (part B)<br />
H: Hediger M. A.<br />
Function, pharmacology<br />
and pathophysiology<br />
of the TRPC1 channel<br />
H: Niggli E.<br />
Physiology, pharmacology<br />
and pathophysiology of the<br />
calcium-activated non-selective<br />
cation TRPM4 channel<br />
H: Abriel H.<br />
Structure, function and pharmacology<br />
of sodium / calcium<br />
exchangers (SLC8, SLC24)<br />
H: Stahlberg H.<br />
Novel sodium/hydrogen<br />
exchanger NHA2 – a quest<br />
for biological function<br />
H: Fuster D.<br />
Structure, function and<br />
pharmacology of anoctamines,<br />
divalent metal ion<br />
transporters and vesicular<br />
neurotransmitter transporters<br />
H: Dutzler R.<br />
Vesicular neurotransmitter<br />
transporters: glutamate and<br />
monoamines<br />
H: Volterra A.<br />
Bezzi P.<br />
Structure and molecular<br />
transport mechanisms of<br />
selected solute transporters<br />
H: Fotiadis D.<br />
Glucose, myo-inositol<br />
and urate transporters<br />
H: Thorens B.<br />
Transporters in pathologies<br />
during pregnancy, part A<br />
H: Surbek D.<br />
Baumann M.<br />
Transporters in pathologies<br />
during pregnancy, part B<br />
H: Albrecht C.<br />
Ligand design for TRP<br />
channels and glutamate,<br />
monoamine, metal ion,<br />
vitamin C, nucleobase and<br />
myo- inositol transporters<br />
H: Reymond J.-L.<br />
Ligand development<br />
for the vesicular monoamine<br />
transporter VMAT2 and the<br />
putative endocannabinoid<br />
transporter<br />
H: Altmann K.-H.<br />
Development of selective<br />
fluorescence- and photoaffinity-labeled<br />
ligands<br />
for transporters and channels<br />
H: Lochner M.<br />
Screening assay development<br />
and targeting of the<br />
endocannabinoid transporter<br />
H: Gertsch J.<br />
Structural and mechanistic<br />
studies of lipid/drug<br />
transporters and their<br />
therapeutic relevance<br />
H: Locher K.<br />
Role of canalicular lipid<br />
secretion in acquired forms<br />
of cholestasis<br />
H: Stieger B.<br />
Role of ion transporter<br />
TRPV6 and other transporters<br />
in bone homeostasis<br />
H: Hofstetter W.<br />
Facilities<br />
Screening and assay development<br />
facility<br />
H: Hediger M. A.<br />
Bioinformatics facility<br />
H: Anderle P.<br />
CardioMet Mouse Metabolic<br />
Evaluation Facility (MEF)<br />
H: Thorens B.<br />
Bone and Mineral Research<br />
Facility<br />
H: Hofstetter W.<br />
Natural product libraries<br />
facility<br />
H: Gertsch J.<br />
Electron Crystallography<br />
facility<br />
H: Stahlberg H.<br />
<strong>NCCR</strong> Management<br />
Director<br />
Hediger Matthias A., Prof.<br />
phone: + 41(0)31 631 41 29<br />
matthias.hediger@ibmm.unibe.ch<br />
Deputy Director<br />
Reymond Jean-Louis, Prof.<br />
phone: +41 (0)31 631 43 25<br />
jean-louis.reymond@ioc.unibe.ch<br />
Scientific Officer<br />
Weisstanner Martin, Dr.<br />
phone: +41 (0)31 631 40 95<br />
martin.weisstanner@ibmm.unibe.ch<br />
Finances<br />
Knigge Salis Carsten, Dr.<br />
phone: +41 (0)31 631 36 22<br />
carsten.kniggesalis@ibmm.unibe.ch<br />
Communications<br />
Reymond Martine, Chem. Eng.<br />
EPFL, MBA<br />
phone: +41 (0)31 631 40 95<br />
martine.reymond@ibmm.unibe.ch<br />
Knowledge and Technology<br />
Transfer<br />
Reymond Martine, Chem. Eng.<br />
EPFL, MBA<br />
Advancement of Women<br />
Reymond Martine, Chem. Eng.<br />
EPFL, MBA<br />
Education and Training<br />
Niggli Ernst, Prof.<br />
phone: +41 (0)31 631 87 30<br />
niggli@pyl.unibe.ch<br />
Address<br />
<strong>NCCR</strong> TransCure<br />
Institute for Biochemistry<br />
and Molecular Medicine<br />
University of Bern<br />
Bühlstrasse 28, 3012 Bern<br />
Web Address<br />
www.transcure.org<br />
Public Relations<br />
• TransCure Translations<br />
Newsletter<br />
• Newspaper articles<br />
and press releases<br />
• BioMedical Transporters<br />
Conference Series:<br />
www.bioparadigms.org<br />
<strong>Guide</strong> <strong>2013</strong> | 31
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