NCCR Guide 2013 - Schweizerischer Nationalfonds (SNF)

Topics
Cancer cells are defective
in basic processes controlling
cell differentiation
and proliferation, genome
stability and programmed
cell death. They acquire
capacities to invade tissues,
to stimulate angiogenesis,
and to elicit innate and in
some instances specific immune
responses. The Swiss
Institute for Experimental
Cancer Research (ISREC),
an institute of the School of
Life Sciences of the Ecole
Polytechnique Fédérale de
Lausanne (EPFL), forms
together with several partner
institutes (Ludwig Institute
for Cancer Research,
Department of Biochemistry
of the University of
Lausanne, Swiss Institute
of Bioinformatics) a biomedical
research network
in Lausanne. The research
Petrova Tatiana, Prof.
Romero Pedro, Prof.
Rüegg Curzio, Prof.
Rufer Nathalie, Dr.
Speiser Daniel, Prof.
Stamenkovic Ivan, Prof.
Swartz Melody, Prof.
Centre pluridisciplinaire d‘oncologie, Lausanne
Ludwig Institut for Cancer Research, Epalinges
Université Fribourg, Département de médecine
Centre pluridisciplinaire d‘oncologie, Lausanne
Ludwig Institut de Recherches sur le Cancer, Epalinges
Centre Hospitalier Universitaire Vaudois, CHUV, Lausanne
Institut of Bioengineering, EPF Lausanne
Partner Institutions
Ludwig Institute for Cancer Research LICR, Lausanne Branch
Department of Biochemistry of the University of Lausanne DB, UNIL
Swiss Institute of Bioinformatics SIB, Lausanne Branch
Centre Pluridisciplinaire d’Oncologie CePO
Centre Hospitalier Universitaire Vaudois CHUV
Department of Medecine, University of Fribourg
Department of Biomedicine, University of Basel
Members of the Advisory Board
Tumor-Host Interaction and Apoptosis
Ashkenazi Avi, Prof.
Carmeliet Peter, Prof.
Rommelaere Jean, Prof.
Genentech Inc., San Francisco, US
Catholic University of Leuven, BE
Deutsches Krebsforschungszentrum DKFZ, Heidelberg, DE
DNA-Microarrays, Bioinformatics and Tumor Specific Gene Expression
Ansorge Wilhelm, Prof.
European Molecular Biology Laboratory EMBL, Heidelberg, DE
Collins Peter, Prof.
University of Cambridge, GB
Guha Abhijit, Prof.
University of Toronto, CA
Liu Edison, Prof.
Genome Institute of Singapore, SG
Van‘t Veer Laura, Dr.
Netherlands Cancer Institute NKI, Amsterdam, NL
Immunotherapy
Greenberg Philip, Prof.
Lanzavecchia Antonio, Prof.
Melief Cees J. M., Prof.
focuses on different aspects
of basic tumor biology and
the host response to cancer.
Work at ISREC centers
on the discovery of genes
that play important roles
in tumorigenesis and metastasis,
using genetic approaches
in human cancer
cell lines and model organisms.
A research module integrating
projects from the
EPFL and the Universities
of Basel and Fribourg investigates
the role of blood
and lymph vessels in tumor
invasion and metastasis.
Other groups in the ISREC
and the Ludwig Institute for
Cancer Research elucidate
the mechanisms that control
immune responses to
cancer. Research projects
in external institutes and
clinics, also in other parts
of Switzerland, complement
the research portfolio
of this cancer research program.
The projects of the NCCR
Molecular Oncology form
a basis for the design of
novel approaches to cancer
therapy, and the program
provides us with the means
to explore such prospects,
through cooperation with
our partners in different
University hospitals. The
NCCR has also been essential
for supporting technology
development and core
facilities necessary for such
clinically oriented research.
Finally, the program provides
training opportunities
for MD/PhDs to foster
the development of translational
oncology in Switzerland.
University of Seattle & Fred Hutchinson Cancer Research
Center, US
Istituto di Ricerca in Biomedicina IRB, Bellinzona, CH
Leiden University, NL
Third Party Cooperation
Programmes
• SmArt (FP7)
Research Institutions
• A.I.Virtanen Institute for
Molecular Sciences, University
of Kuopio, FI
• Biobix: lab for computational
genomics & bioinformatics,
University of Gent, Gent, BE
• Brain Tumor Group,
European Organization
for Research and Treatment
of Cancer, Brussels, BE
• Center for Human Genetics and
Dept. of Gastro-Enterology,
University Hospital
Gasthuisberg, Leuven, BE
• Center for Molecular Medicine,
University of Köln, Köln, DE
• Centre Hospitalier Universitaire
Vaudois, Lausanne, CH
• CIBM, Centre Hospitalier
Universitaire Vaudois,
Lausanne, CH
• Department for Biochemistry
and Molecular Biology, University
of Chicago, Chicago, US
• Department of Molecular
Embryology, Max-Planck
Institute for Immunobiology,
Freiburg, DE
• Department of Neuropathology,
Department of Neuropathology,
Valore, IN
• Department of Pathology, University
of Geneva, Geneva, CH
• Department of Physics of
Complex Systems, Weizmann
Institute of Science, Rehovot, IL
• Department of Surgical
Oncology, Erasmus University
Hospital, Rotterdam, NL
• Department Oncological
Sciences, University of Torino,
Torino, IT
• IFOM-IEO, Milan, IT
• Impact du Microenvironnement
sur l`Angiogenèse et l`Invasion
Tumorale, Centre de Recherche
INSERM, Strasbourg, FR
• Institut contre l’arthrose, Lausanne,
CH
• Institute of Molecular Medicine,
University of Lisbon, PT
• MD Cancer Centre, The University
of Texas, Houston, US
• Medical Biochemistry and Molecular
Biology, Oulu Center for
Cell-Matrix Research, Oulou, FI
• Molecular Life Sciences,
Universität Frankfurt, DE
• Neurosurgery, Centre
Hospitalier Universitaire
Vaudois, Lausanne, CH
• Pathology, Université de
Fribourg, CH
• Pharmaceutical Biochemistry,
University of Geneva,
Geneva, CH
• Service de medécine nucleaire,
Centre Hospitalier Universitaire
Vaudois, Lausanne, CH
Guide 2013 | 9