Simulation of Clinical Trials with Mathematical Models ... - CBI
Simulation of Clinical Trials with Mathematical Models ... - CBI
Simulation of Clinical Trials with Mathematical Models ... - CBI
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Topics<br />
• Rationale, mechanisms, and challenges <strong>of</strong> simulating<br />
clinical trials<br />
• Archimedes Model<br />
– Overview<br />
– Validation<br />
– Capabilities and applications<br />
• Case Studies<br />
– DPP expansion and extension<br />
– A-L-L<br />
– Results <strong>of</strong> 20 simulated trials <strong>of</strong> interventions for<br />
cardiometabolic risk<br />
3