What Is A Free Radical - Ãstav lÃ©kaÅskÃ© chemie a biochemie

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…and very complex Oxidative stress • Levels of reactive oxygen species are kept within certain limits by mechanisms of antioxidant defence • Oxidative stress occurs if the oxidant/antioxidant balance shifts to oxidation 18
Antioxidant defence • prevention of ROS/RNS formation (regulation of producing enzymes, sequestration of metals) • scavenging, trapping and quenching of radicals • reparation systems (phospholipases, proteasome, DNA repair) Antioxidant in food chemistry • Reducing agent capable of terminating chain reaction of lipid peroxidation …“chain-breaking” ... • E.g.: – Butylated hydroxytoluene (BHT) – Butylated hydroxyanisol (BHA) – Tocopherol (Vitamin E) 19
Page 1 and 2: Reactive Oxygen Species in the Body
Page 4 and 5: Spin restriction of dioxygen • No
Page 6 and 7: Reactive oxygen species (ROS, ‘ox
Page 8 and 9: Origin of superoxide from oxyhemogl
Page 10 and 11: Hydroxyl radical • Formation in t
Page 12 and 13: NO causes relaxation of smooth musc
Page 14 and 15: Further fate of lipid peroxides Ion
Page 16 and 17: Beneficial ROS: Respiratory burst o
Page 20 and 21: Antioxidant defence of human body
Page 22 and 23: Mitochondria originated from phagoc
Page 24 and 25: Glutathione (GSH/GSSG) • tripepti
Page 26 and 27: Peroxiredoxin/Thioredoxin • Recen
Page 28 and 29: ICT ECT Superoxide Peroxide Fe/Cu S
Page 30 and 31: Ascorbate in the body: • Main fun
Page 32 and 33: Antioxidant defence V Stress respon
Page 34: Free radicals in pathogenesis of hu

What Is A Free Radical - Ãstav lÃ©kaÅskÃ© chemie a biochemie

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What Is A Free Radical - Ãstav lÃ©kaÅskÃ© chemie a biochemie