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Quantitative analysis of EEG signals: Time-frequency methods and ...

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ln d(t) ln C + t (50)<br />

This gives a set <strong>of</strong> parallel lines for the dierent embedding dimensions, <strong>and</strong> the<br />

largest Lyapunov Exponent can be calculated as the mean slope, averaging all the<br />

embedding vectors.<br />

Lyapunov exponents are very sensible to the election <strong>of</strong> the time lag, the embedding<br />

dimension <strong>and</strong> especially to the election <strong>of</strong> the evolution time. If the evolution time is too<br />

short, neighbor vectors will not evolve enough in order to obtain relevant information.<br />

If the evolution time is too large, vectors will \jump" to other trajectories thus giving<br />

unreliable results.<br />

5.3 Stationarity<br />

Due to the fact that Chaos <strong>methods</strong> require stationary <strong>signals</strong> <strong>and</strong> <strong>EEG</strong>s are known to<br />

be highly non stationary, I will briey discuss this topic <strong>and</strong> I will propose a criterion <strong>of</strong><br />

stationarity. In principle, non-stationarity means that characteristics <strong>of</strong> the time series,<br />

such as the mean, variance or power spectra, change with time. More technically, if we<br />

have a time series <strong>of</strong> discrete observed values fx 1 x 2 :::x N g, stationarity means that<br />

the joint probability distribution function f 12 (x 1 x 2 ) depends only on the time dierences<br />

jt 1 ; t 2 j <strong>and</strong> not on the absolute values t 1 <strong>and</strong> t 2 (Jenkins <strong>and</strong> Watts, 1968). Statistical<br />

tests <strong>of</strong> stationarity have revealed a variety <strong>of</strong> results in <strong>EEG</strong>s, <strong>and</strong> estimates <strong>of</strong><br />

stationary epochs range from some seconds to several minutes (Lopes da Silva, 1993a).<br />

However, whether or not the same data segment is considered stationary, depends on<br />

the problem being studied <strong>and</strong> the type <strong>of</strong> <strong>analysis</strong> to be performed.<br />

In the case <strong>of</strong> <strong>EEG</strong>s, due to the large amount <strong>of</strong> data needed for the application <strong>of</strong><br />

the non linear dynamic <strong>methods</strong>, strict stationarity is almost impossible to achieve. This<br />

problem has brought agreatvariety <strong>of</strong> results exposed by dierent authors (Basar, 1990<br />

Basar <strong>and</strong> Bullock, 1989). A less restrictive requirement, called \weak stationarity" <strong>of</strong><br />

order n, is that the moments up to some order n are fairly stable with time. If the<br />

probability distribution <strong>of</strong> a signal is Gaussian, it can be completely characterized by its<br />

mean ( m ), its variance ( 2 ) <strong>and</strong> its autocorrelation function. In this case, second order<br />

stationarity ( n = 2 ), plus an assumption <strong>of</strong> normality, is enough to assure complete<br />

stationarity (Jenkins <strong>and</strong> Watts, 1968). Consequently, in order to check for stationarity<br />

<strong>of</strong> the <strong>EEG</strong> segments to be used for <strong>analysis</strong>, the following procedure was used (Blanco<br />

et al., 1995a).<br />

1. The total <strong>EEG</strong> time series was divided in bins with a xed number <strong>of</strong> data. The<br />

election <strong>of</strong> the bin length depends on the type <strong>of</strong> data <strong>and</strong> on the <strong>analysis</strong> to be<br />

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