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ANZCA Bulletin June 2011 - Australian and New Zealand College of ...

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Airway Management<br />

As the third report on airway<br />

disasters appears in this edition <strong>of</strong><br />

the <strong>Bulletin</strong> it is timely to review the<br />

groundbreaking project <strong>of</strong> the 4th<br />

National Audit Project (NAP4) <strong>of</strong> the<br />

Royal <strong>College</strong> <strong>of</strong> Anaesthetists (RCoA).<br />

This collaborative study, involving the<br />

RCoA <strong>and</strong> the Difficult Airway Society<br />

(DAS), was a one-year prospective<br />

audit <strong>of</strong> serious airway complications<br />

in anaesthesia, intensive care <strong>and</strong><br />

emergency departments for all 309<br />

National Health Service Hospitals in<br />

the UK, with an expert panel being<br />

appointed to assess every report.<br />

The full report is available on the<br />

RCoA website 1 <strong>and</strong> the British Journal<br />

<strong>of</strong> Anaesthesia has both an excellent<br />

editorial 2 <strong>and</strong> two articles reporting<br />

on complications related to general<br />

anaesthesia 3 as well as to intensive care<br />

<strong>and</strong> emergency departments. 4<br />

Major complications related to<br />

general anaesthesia were identified in<br />

a total <strong>of</strong> 133 cases which the authors<br />

assess as 1/22000 cases, assuming an<br />

estimated denominator <strong>of</strong> 2.9 million<br />

general anaesthetics administered<br />

annually. During this one year period<br />

there were 13 deaths <strong>and</strong> three cases<br />

<strong>of</strong> irreparable brain damage. Even<br />

with this carefully planned survey<br />

the authors concede that there may<br />

be under-reporting <strong>and</strong> that as few<br />

as 25 per cent were reported. This<br />

would certainly be the experience <strong>of</strong><br />

the Victorian Consultative Council on<br />

Anaesthetic Mortality <strong>and</strong> Morbidity<br />

(VCCAMM). The indicators for inclusion<br />

in the study were death, brain damage,<br />

the need for an emergency surgical<br />

airway, unplanned admission to ICU<br />

or prolongation <strong>of</strong> stay in ICU. Obesity<br />

was considered an important risk factor<br />

<strong>and</strong> was defined as a body mass index<br />

<strong>of</strong> >30 kg m -2 which was identified in<br />

42 per cent <strong>of</strong> reports. Also <strong>of</strong> note was<br />

that over half <strong>of</strong> the patients were ASA<br />

P1-2 <strong>and</strong> under the age <strong>of</strong> 60 <strong>and</strong> most<br />

events occurred during elective surgery<br />

while under the care <strong>of</strong> consultant<br />

anaesthetists.<br />

The most common primary airway<br />

problems in anaesthesia were failed<br />

intubation, aspiration <strong>of</strong> gastric<br />

contents <strong>and</strong>, importantly, problems<br />

related to tracheal extubation or<br />

removal <strong>of</strong> a supraglottic airway.<br />

Aspiration <strong>of</strong> gastric contents was the<br />

single most common cause <strong>of</strong> death <strong>and</strong><br />

occurred in 14 cases with a supraglottic<br />

airway <strong>and</strong> eight cases with a tracheal<br />

tube, indicating that risks <strong>of</strong> aspiration<br />

have not always been adequately<br />

assessed when a supraglottic airway<br />

is employed.<br />

In 58 cases an emergency surgical<br />

airway was attempted. Twenty-nine<br />

<strong>of</strong> these cases underwent surgical<br />

tracheostomy as a primary event while<br />

cricothyrotomy was attempted in 29, <strong>of</strong><br />

which 15 failed <strong>and</strong> required surgical<br />

rescue: cricothyroidotomy performed by<br />

anaesthetists had a high rate <strong>of</strong> failure.<br />

The second section <strong>of</strong> the NAP4<br />

report relates to airway incidents<br />

in emergency or intensive care<br />

departments. Inclusion criteria were<br />

the same as for the anaesthesia related<br />

events but also included events<br />

occurring during transport between<br />

departments. Thirty-six reports<br />

concerned patients in ICU <strong>and</strong> 15 in the<br />

emergency department. Of these there<br />

were 18 deaths <strong>and</strong> four cases <strong>of</strong> brain<br />

damage in ICU patients <strong>and</strong> four in the<br />

emergency department.<br />

Of the ICU patients 61 per cent were<br />

aged less than 60 <strong>and</strong> 22 per cent were<br />

ASA P1-2. Invasive ventilation had<br />

been established in 19 patients <strong>and</strong> non<br />

invasive in eight <strong>and</strong> there was a BMI <strong>of</strong><br />

>30kg m -2 in 47 per cent. Of note was the<br />

occurrence <strong>of</strong> 46 per cent <strong>of</strong> incidents<br />

out <strong>of</strong> hours with many managed by<br />

junior doctors without training in<br />

airway management. This problem was<br />

less common in emergency departments<br />

where anaesthetists were more <strong>of</strong>ten<br />

available <strong>and</strong> where emergency<br />

consultants were on duty 24 hours a day.<br />

In ICU the main primary airway events<br />

were tracheostomy related problems,<br />

tracheal tube misplacement <strong>and</strong><br />

failed intubation <strong>and</strong> there were three<br />

unrecognised oesophageal intubations,<br />

two <strong>of</strong> which were fatal. Poor planning<br />

<strong>and</strong> training were identified in many <strong>of</strong><br />

these cases as well as the unavailability<br />

<strong>of</strong> equipment, notably capnography.<br />

In recent years the majority <strong>of</strong> airway<br />

incidents reported to VCCAMM have<br />

occurred in areas outside the operating<br />

theatre <strong>and</strong> VCCAMM has repeatedly<br />

recommended that whenever the patient<br />

is intubated <strong>and</strong> there is artificial<br />

ventilation, capnography is essential.<br />

NAP4 has claimed that it is likely that<br />

over 79 per cent <strong>of</strong> airway deaths in<br />

ICU could have been prevented had<br />

continuous capnography been used.<br />

Even now it is not known how many<br />

intensive care units in Australia still do<br />

not have the capability <strong>of</strong> continuous<br />

capnography in all ventilated patients.<br />

However it must be recognised that<br />

equipment alone is not sufficient <strong>and</strong><br />

that there must also be training in the<br />

interpretation <strong>of</strong> absent or altered CO2<br />

waveforms <strong>and</strong> that the possibility <strong>of</strong><br />

equipment error is small <strong>and</strong> must not<br />

distract from the need for urgent action.<br />

NAP4 is a seminal project with<br />

enormous implications for improvement<br />

in airway management, particularly<br />

outside the operating theatres, <strong>and</strong><br />

the articles in the British Journal <strong>of</strong><br />

Anaesthesia are highly recommended<br />

reading as well as the web site <strong>of</strong> the<br />

RCoA. 1<br />

Dr Patricia Mackay<br />

Communication/Liaison Portfolio<br />

References<br />

1. RCoA Website. www.rcoa.ac.uk/index.<br />

aspPageID-1089<br />

2. Norris AM, Hardman JG, Asai T Editorial:<br />

A firm foundation for progress in airway<br />

management. Br J A naesth 2111;<br />

106: 513-516<br />

3. Cook TM, Woodall N, Freck C. Major<br />

Complications <strong>of</strong> Airway Management in<br />

the UK. Part 1 Anaesthesia. Br J Anaesth<br />

2111; 106: 617-31<br />

4. Cook TM, Woodall N, Harper J, Benger<br />

J. Major Complications <strong>of</strong> Airway<br />

Management in the UK. Part 2: intensive<br />

care <strong>and</strong> emergency departments.<br />

Br J Anaesth <strong>2011</strong>; 106: 632-42<br />

<strong>ANZCA</strong> <strong>Bulletin</strong> <strong>June</strong> <strong>2011</strong> 63

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