TUMOR IMMUNOLOGY.pdf
TUMOR IMMUNOLOGY.pdf
TUMOR IMMUNOLOGY.pdf
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Immune defects in T cells in cancer<br />
• Alterations in the expression of signal transduction<br />
molecules in immune cells.<br />
• Loss of CD 3ζ chain. TCR-CD3 complex. It functions<br />
as a single transducer upon antigen binding.<br />
• Receptor-mediated apoptosis of T cells contributes to<br />
T cell dysfunction.
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