TUMOR IMMUNOLOGY.pdf

Main Mechanisms of
Immunotherapy
• Stimulating the antitumor response, either by increasing
the number of effector cells or by producing soluble
mediators.
• Decreasing suppressor mechanisms.
• Altering tumor cells to increase their immunogenicity and
make them more susceptible to immunologic defences.
• Improving tolerance to cytotoxic drugs or radiotherapy,
p g y g py,
such as stimulating bone marrow function with GM-CSF.