TUMOR IMMUNOLOGY.pdf
TUMOR IMMUNOLOGY.pdf
TUMOR IMMUNOLOGY.pdf
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Potential mechanisms for synergy displayed by combined blocking<br />
hypoxia pathway and B7.1-mediated immunotherapy<br />
NK<br />
Apoptosis<br />
Tumor<br />
cell<br />
v<br />
v<br />
Tumor<br />
cell<br />
v<br />
Tumor<br />
cell<br />
B7.1<br />
Necrosis<br />
B7.1+AS-HIF<br />
Activates<br />
NK cells<br />
AS-HIF<br />
Anti-angiogenesis<br />
+ hsp70- tumor<br />
Antigen<br />
Glycolysis<br />
B7.1 APC MHCI<br />
CD28<br />
T cell<br />
MHCII<br />
CD28<br />
Tumor C<br />
cell<br />
B7.1<br />
MHCI<br />
T cell<br />
Proliferation<br />
& CTLmediated<br />
killing<br />
MHCII<br />
Heat-shock<br />
di driven antitumor<br />
immunity<br />
Cell vitality<br />
Immune suppressive<br />
elements<br />
Tumor<br />
Cell<br />
Apoptosis
Change language