impact of latex and plant extract of and the recovery of latex toxicity ...

Brain :
Normal Structure
The study of brain sections of the control fish showed the mode of arrangement of
different layers in the cerebral cortex. It consists of an outer region, the molecular
iayer and an inner region the granular layer. At the junction between the two are the
large purkinji cells that are characteristic of the cerebellum. Optic tectum lies within
the molecular layer. The cells of the molecular layer are widely spaced, in contrast,
the cells of granular layer are closely packed. The purkinjl cells are large and
extends to the molecular layer. The granular layer consists of many small cells called
granule cells. They appear as dark bodies. The granular layer shows clear areas
callcd glomureli.Nucleus genicultaum is present within this. To the centre of the
cortex lies the nucleus rotundus. Besides the purkinji, within the granular layer, is
the small opening called torus semicircularis efferent. (platel and 2).
Changes due to exposure to sublethal concentrations
The outer layer of the cortex was ruptured at many polnts .Remarkable difference
was noticed in TU3 treated fish and the atrophy of the malecular layer was deserved
leavmg intracellular spaces.Nucleus rotundus of the TU3 treated brain was
degenerated.Necrosis of the neurofibrillar region had also been observed. The
granular layer also became atrophied in TU2.A complete change in the cellular make
up due to vascular dilation in the granular layer had been observed. Cells lying in the
molecular layer degenerated especially in the brain treated with TU2. The Purkinji
cells differentiating the molecular layer get closely packed in TU land TU2, the
granular layer becomes reduced in size and cells seemed to be more adjacently
packed. The torus semicircularis efferent when compared with control was found to
be widened inTUl treated fish brain section and also in TU2 and TU3 treated one. In
contrast to the control section, the various layers of the brain cortex were marked in