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Tuesday, april 27 anatomy - Experimental Biology

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iochemistry<br />

B324 905.5 Simultaneous quantification of histone<br />

acetylation, methylation and ubiquitination at multiple sites<br />

by LC/MS/MS-MRM. K. Zhang, M. Schrag, A. Darmanto, A.<br />

Semotiuk, G. Xu and W. Kirsch. Loma Linda Univ. and Inst. of<br />

Biochem. and Cell Biol., Shanghai.<br />

906. Recombinant DNA Technology<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 1:00 p m-2:10 p m<br />

B325 906.1 Lentiviral vector expressing Nef as a tool to<br />

study HIV neuropathology. E.A. Cruz and R.J. Noel. Ponce<br />

Sch. of Med., PR.<br />

B326 906.2 Characterization of bovine 20a-HSD gene<br />

promoter. K-S. Min, N. Purevjargal and M-H. Kang. Hankyong<br />

Natl. Univ. and Hoseo Univ., Republic of Korea.<br />

B3<strong>27</strong> 906.3 Construction of the broad range cloning vector<br />

pHC60mCherry: plant-microbe interaction applications. G.A.<br />

Ramirez, N. Vozza, A. Zorreguieta and M. Tolmasky. California<br />

State Polytech Univ., Pomona, Inst. Fndn. Leloir, Buenos Aires<br />

and California State Univ., Fullerton.<br />

907. Chemical <strong>Biology</strong> and Drug Discovery<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 1:00 p m-2:10 p m<br />

B328 907.1 Fluorescent intercalator displacement as a tool<br />

for RNA-ligand discovery. P.N. Asare-Okai and C.S. Chow.<br />

Wayne State Univ.<br />

B329 907.2 Chemical protein modification: tools for<br />

synthetic biology. G. Bernardes. Max Planck Inst., Berlin.<br />

B330 907.3 Structure based design and structure activity<br />

relationship of new reversible peptides inhibitors of thrombin<br />

derived from D-Phe-Pro-Arg substrate peptide. C.C. Clement<br />

and M. Philipp. Albert Einstein Col. of Med. and Lehman Col.,<br />

CUNY.<br />

B331 907.4 Thermal stability assay for glaucoma-causing<br />

myocilin mutants using maltose binding fusion protein. J.L.<br />

Harris, R. Lieberman, J.N. Burns and S. Orwig. Capital Univ.<br />

OH and Georgia Tech.<br />

B332 907.5 Shape-shifting proteins with a potential link to<br />

drug side effects. S.H. Lawrence, T. Selwood, U.D. Ramirez,<br />

L. Stith and E.K. Jaffe. Fox Chase Cancer Ctr.<br />

B333 907.6 A screening assay for Z a1-antitrypsin<br />

aggregation. M.J. LeMieux, E. Rowe and V. Berthelier. Univ.<br />

of Tennessee Grad. Sch. of Med.<br />

B334 907.7 Imaging the distribution of carbon-11 labeled<br />

rifampicin, isoniazid and pyrazinamide in baboons using PET.<br />

L. Liu, J.M. Hooker, J.S. Fowler and P.J. Tonge. Stony Brook<br />

Univ. and Brookhaven Natl. Lab.<br />

B335 907.8 Development of a peptide nucleic acid-based<br />

siRNA delivery system. T.U. Naik and M.O. Sullivan. Univ. of<br />

Delaware.<br />

B336 907.9 Screen for chemical modulators of the laminininduced<br />

clustering of dystroglycan reveals novel inhibitors of<br />

aquaporin-4 polarized distribution in astrocytes. G.P. Noel, S.<br />

Stevenson and H. Moukhles. Univ. of British Columbia.<br />

B337 907.10 Hyperactive mice show elevated D2High<br />

receptors, a model for schizophrenia: calcium/calmodulindependent<br />

kinase II alpha knockouts. G. Novak and P. Seeman.<br />

Univ. of Toronto.<br />

B338 907.11 SAR studies of diphenyl ethers, potential antituberculosis<br />

drugs as InhA inhibitors. P. Pan, N. Liu, R.A.<br />

Slayden and P. Tonge. Stony Brook Univ. and Colorado State<br />

Univ.<br />

B339 907.12 Binary selectivity for HCV NS3/4A protease<br />

versus host proteases via irreversible inactivation at a noncatalytic<br />

cysteine. R.C. Petter, M. Hagel, D. Niu, T. St. Martin,<br />

M.P. Sheets, L. Qiao, H. Bernhard, R. Karp, Z. Zhu, M.T.<br />

Labenski, P. Chaturvedi, M. Nacht, W. Westlin and J. Singh.<br />

Avila Therapeut., Waltham, MA.<br />

B340 907.13 Allosteric modulators of a protein kinase via<br />

disulfide-trapping. J.D. Sadowsky and J. Wells. UCSF.<br />

B341 907.14 Selection of aptamers against live E. coli cells<br />

using cell SELEX. S.L. Shipley, E. White and S-K. Kim. Baylor<br />

Univ.<br />

B342 907.15 Using a combination of chemical and systems<br />

biological approaches for defining a mechanism by which a<br />

novel anti-aging compound greatly extends yeast longevity. V.<br />

Titorenko, A. Goldberg, S. Bourque, A. Beach, M. Burstein,<br />

V. Richard, P. Kyryakov, C. Gregg, T. Boukh-Viner, M. Juneau<br />

and A. Glebova. Concordia Univ., Canada.<br />

908. Chemical <strong>Biology</strong>: Evolution,<br />

Engineering and Design<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 1:00 p m-2:10 p m<br />

B343 908.1 Physical models of enzymes engineered for<br />

biofuel cells: 2010 Pingry School SMART team project. T.S.<br />

Hata, S. Banta, E. Campbell, T. Herman, C. Ha, E. Kong, F. Ma,<br />

D. Ober, M-L. Picard, D. Sukhin, D. Sun, R. Vollbrechthausen,<br />

C. Wang, E. Xiao and D. O’Mara. Pingry Sch., Martinsville, NJ,<br />

Columbia Univ. and Milwaukee Sch. of Engin.<br />

B344 908.2 Combinatorial design of a four-helix bundle<br />

protein using high-throughput thermal scanning. T.J. Magliery,<br />

J.J. Lavinder, S.B. Hari, C. Nguyen and S. Sen. Ohio State<br />

Univ.<br />

B345 908.3 Novel transformations in the biosynthesis of<br />

the marine-derived antibiotic marinopyrrole. K.S. Ryan, T.A.M.<br />

Gulder and B.S. Moore. UCSD.<br />

909. Drug Resistance<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 1:00 p m-2:10 p m<br />

<strong>Tuesday</strong><br />

B346 909.1 Investigation of class I integron presence and<br />

subsequent variable region characterization of 15 clinical<br />

isolates from Buenos Aires, Argentina. J. Kim, J. Mercado, D.<br />

Centron and M. Tolmasky. California State Univ., Fullerton<br />

and Univ. of Buenos Aires.<br />

B347 909.2 Biophysical basis for TetX mediated antibiotic<br />

resistance. K. Walkiewicz, K. Lau and Y. Shamoo. Rice Univ.<br />

<strong>27</strong>2

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