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Tuesday, april 27 anatomy - Experimental Biology

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tuesday<br />

D101 978.21 Differences in the cardiac proteome in rats<br />

selected for either low or high running capacity. J. Burniston,<br />

J. Kenyani, J. Wastling, L. Koch and S.L. Britton. Liverpool<br />

John Moores Univ., Sch. of Vet. Sci., Univ. of Liverpool and<br />

Univ. of Michigan.<br />

D102 978.22 Diosgenin supress cardiac apoptosis and<br />

enhance survival pathway in ovariectomized rats. S-D. Lee, C-Y.<br />

Tasi, H-C. Ou and C-Y. Huang. China Med. Univ., Taiwan.<br />

D103 978.23 The ZDSD, a new rat model of metabolic<br />

syndrome: evidence of cardiovascular disease. C.S. Packer,<br />

L.M. Meulen, A.M. Boice, K. Coy and R.G. Peterson. Indiana<br />

Univ. Sch. of Med. and PreClinOmics, Indianapolis.<br />

D104 978.24 The ZDSD, a new rat model of metabolic<br />

syndrome: altered arterial muscle mechanics. C.S. Packer,<br />

A.M. Boice, L.M. Meulen, K. Coy and R.G. Peterson. Indiana<br />

Univ. Sch. of Med. and PreClinOmics, Indianapolis.<br />

D105 978.25 Niacin reduces renal damage and insulin<br />

insensitivity in Charles River obese SHR (SHROB/cp): a model<br />

of the metabolic syndrome. Y-J. Kang, T. Manero, S. Levine,<br />

D. Owens, P. Chander and C. Stier. New York Med. Col.,<br />

Nathan Kline Inst., Orangeburg, NY and Charles River Labs.,<br />

Wilmington, MA.<br />

D106 978.26 Telmisartan improves cognitive function<br />

through the increase in neurotrophic factor and inhibition of<br />

apoptosis in hippocampus of rats with metabolic syndrome. T.<br />

Kishi, Y. Hirooka and K. Sunagawa. Kyushu Univ. Grad. Sch.<br />

of Med. Sci., Japan.<br />

979. Cerebral Circulation I<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:45 p m-3:00 p m<br />

D107 979.1 Canrenoic acid, a mineralocorticoid receptor<br />

antagonist, attenuates resistance artery remodeling in strokeprone<br />

spontaneous hypertensive rats. P.W. Pires, J.L. McClain<br />

and A.M. Dorrance. Michigan State Univ.<br />

D108 979.2 Postnatal maturation and hypoxic acclimatization<br />

modulate PKG-mediated activation of BK channels in ovine<br />

cerebral arteries. J.M. Williams, S.L. Stockman, T.M. Lincoln<br />

and W.J. Pearce. Loma Linda Univ. Sch. of Med. and Univ. of<br />

Southern Alabama Col. of Med.<br />

D109 979.3 Involuntary breathing movements improve<br />

cerebral oxygenation during apnea struggle phase in elite<br />

divers. Z. Dujic, L. Uglesic, T. Breskovic, Z. Valic, K. Heusser,<br />

J. Marinovic, M. Ljubkovic and I. Palada. Univ. of Split Sch. of<br />

Med., Croatia and Hannover Med. Sch., Germany.<br />

D110 979.4 Inhibition of PPARg during pregnancy causes<br />

inward remodeling of brain parenchymal arterioles. M.J.<br />

Cipolla, S-L. Chan, A.C. Chapman and J.A. Godfrey. Univ. of<br />

Vermont.<br />

D111 979.5 Role of cAMP and cGMP in arachidonic acid<br />

and PGE2-induced cerebral vasodilation in newborn pigs.<br />

A.J. Kanu and C.W. Leffler. Univ. of Tennessee Hlth. Sci. Ctr.,<br />

Memphis.<br />

D112 979.6 PPARa agonists acutely dilate the mouse<br />

middle cerebral artery. N.K. Parelkar, M.Z. Badr and J.<br />

Andresen. Sch. of Med. and Sch. of Pharm., Univ. of Missouri-<br />

Kansas City.<br />

physiology<br />

D113 979.7 Indication for cholinergically mediated cerebral<br />

vasodilatation during static exercise in humans. T. Seifert, J.P.<br />

Fisher, C.N. Young, D. Hartwich, P.J. Fadel and N.H. Secher.<br />

Univ. of Copenhagen, Sch. of Sport & Exercise Sci., Univ. of<br />

Birmingham, UK and Univ. of Missouri-Columbia.<br />

D114 979.8 Akt/Bcl-2 signaling is critical for anti-apoptotic<br />

effects of carbon monoxide against TNF-alpha-mediated<br />

inflammatory damage in cerebral vascular endothelial cells. S.<br />

Basuroy, S. Bhattacharya, C.W. Leffler and H. Parfenova.<br />

Univ. of Tennessee Hlth. Sci. Ctr., Memphis.<br />

980. Coordinate Regulation of Vascular<br />

Smooth Muscle Gene Expression, Cell<br />

Phenotype, and Vessel Function<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:45 p m-3:00 p m<br />

D115 980.1 Cyclosporine upregulates KLF4 in vascular<br />

smooth muscle cells and drives phenotypic modulation in vivo.<br />

D.S. Sinden, S.M. Garvey, D.L. Rose, P.D. Schoppee Bortz,<br />

M.Y. Lee and B.R. Wamhoff. Univ. of Virginia.<br />

D116 980.2 Genomics approach using calcineurin/NFAT<br />

inhibitors to identify novel effectors of vascular smooth muscle<br />

phenotypic modulation. M.Y. Lee, S.M. Garvey and B.R.<br />

Wamhoff. Univ. of Virginia.<br />

D117 980.3 Sphingosine kinase 1 is required for smooth<br />

muscle cell phenotypic modulation in response to vascular<br />

injury. B.R. Wamhoff, T. Matthews, J. Hogan, A. Morris, Y.<br />

Karel, T. Macdonald and K.R. Lynch. Univ of Virginia and<br />

Univ. of Kentucky.<br />

D118 980.4 Nuclear factor of activated T cells regulates<br />

osteopontin expression in arterial smooth muscle in response<br />

to diabetes-induced hyperglycemia. M.F. Gomez, L.M.<br />

Nilsson-Berglund, A.V. Zetterqvist, J. Nilsson-Öhman, M.<br />

Sigvardsson, L.V. Gonzalez-Bosc, M-L. Smith, A. Salehi,<br />

E. Agardh, G. Nordin-Fredrikson, C-D. Agardh, J. Nilsson,<br />

B.R. Wamhoff and A. Hultgårdh-Nilsson. Lund Univ. and<br />

Linköping Univ., Sweden, Univ. of New Mexico and Univ. of<br />

Virginia.<br />

D119 980.5 NFAT5 positively regulates SMaA gene<br />

expression in vascular smooth muscle. J.A. Lemmon, H.M.<br />

Kwon and B.R. Wamhoff. Univ. of Virginia and Univ. of<br />

Maryland Baltimore.<br />

D120 980.6 Interference with peroxisome proliferator<br />

activated receptor gamma in smooth muscle causes aortic<br />

dysfunction via a Rho-kinase-dependent mechanism. C.J.<br />

Pelham, P. Ketsawatsomkron, S. Groh, W.J. de Lange, F.M.<br />

Faraci and C.D. Sigmund. Univ. of Iowa.<br />

D121 980.7 In P14 rat middle cerebral arteries relations<br />

between myogenic tone and cytosolic Ca 2+ are enhanced by<br />

myofilament Ca 2+ sensitization and increased Ca 2+ influx, but<br />

attenuated by high proportions of noncontractile smooth m<br />

S.M. Charles, L. Zhang, M.J. Cipolla, J.N. Buchholz and W.J.<br />

Pearce. Loma Linda Univ. Sch. of Med. and Univ. of Vermont<br />

Col. of Med.<br />

D122 980.8 Phenotypic differences between neonatal and<br />

adult ovine carotid arteries predict reactivity to chronic hypoxia<br />

and VEGF. O.O. Adeoye, S.M. Butler, J.M. Abrassart, E.A.<br />

Mock, J.M. Williams and W.J. Pearce. Loma Linda Univ. Sch.<br />

of Med.<br />

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301

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