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Tuesday, april 27 anatomy - Experimental Biology

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tuesday<br />

C17 956.6 High intravascular pressure decreases<br />

endothelial Ca 2+ pulsars and impairs endothelium-dependent<br />

vasodilation in mouse mesenteric arteries. S.K. Sonkusare,<br />

T.J. Heppner, A.D. Bonev, R.M. Hannah, Y. Talline, M.I.<br />

Kotlikoff and M.T. Nelson. Univ. of Vermont and Cornell Univ.<br />

C18 956.7 Cyclic AMP response element binding protein,<br />

Creb, induces endothelial cell proliferation and angiogenesis<br />

in response to thrombin. K.R. Chava and D. Mehta. Univ. of<br />

illinois at Chicago.<br />

C19 956.8 High molecular weight kininogen regulates<br />

endothelial function. D.S. Kolte, N. Osman, J. Yang and Z.<br />

Shariat-Madar. Univ. of Mississippi.<br />

957. Coronary and Cerebral Artery<br />

Endothelial Function<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:30 p m-2:45 p m<br />

C20 957.1 Rapid estrogen signaling via GPER in human<br />

coronary artery smooth muscle. G. Han, H. Ma, S.A. Barman,<br />

M. Sellers, X. Yu, J.N. Stallone and R.E. White. Texas A&M<br />

Univ. and Med. Col. of Georgia.<br />

C21 957.2 Nitric oxide synthase and soluble guanylyl<br />

cyclase activation are required for hypoxic endotheliumdependent<br />

contractions of the porcine coronary artery. C.K.Y.<br />

Chan, J.C.W. Mak, R.Y.K. Man and P.M. Vanhoutte. Univ. of<br />

Hong Kong.<br />

C22 957.3 Melatonin inhibits NO-induced cGMP<br />

accumulation by increasing PDE5 phosphorylation in coronary<br />

arteries. P. Shukla, A. Grazul-Bilska and S.T. O’Rourke.<br />

North Dakota State Univ.<br />

C23 957.4 Coronary endothelium: new pharmacological<br />

target for heart hypertrophy/failure. X. Sun and D.D. Ku. Univ.<br />

of Alabama at Birmingham.<br />

C24 957.5 Adiponectin is secreted by vascular smooth<br />

muscle cells and regulates muscle contractile phenotype. M.<br />

Ding, R.J. Wagner and K.A. Martin. Dartmouth Col. and Yale<br />

Univ.<br />

C25 957.6 Regulation of cerebral blood flow by hydrogen<br />

sulfide. G. Ahmed, A.O. Oyekan and M.A. Yakubu. Texas<br />

Southern Univ. Col. of Pharm. & Hlth. Sci. and Texas Southern<br />

Univ.<br />

C26 957.7 Possible involvement of cytoskeletal reorganization<br />

in PKC-induced cerebroarterial constriction. A.F. El-<br />

Yazbi. Univ. of Calgary.<br />

958. Role of Adenosine Receptors in<br />

Vascular Function<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:30 p m-2:45 p m<br />

C<strong>27</strong> 958.1 Role of A 1<br />

adenosine receptors in vascular<br />

reactivity and inflammation in a murine model of allergic asthma.<br />

D.S. Ponnoth, A. Nadeem, S. Tilley and S.J. Mustafa. West<br />

Virginia Univ. and Univ. of North Carolina at Chapel Hill.<br />

C28 958.2 Evidence for the role of A 2B<br />

adenosine receptor<br />

in the regulation of vascular tone using A 2B<br />

KO mice. M. Sharifi<br />

Sanjani, D.S. Ponnoth, K. Roush, S. Tilley and S.J. Mustafa.<br />

West Virginia Univ. and Univ. of North Carolina at Chapel Hill.<br />

pHarmacology<br />

C29 958.3 Exaggerated vasoconstriction depends on<br />

w-hydroxyylase through adenosine A 1<br />

receptor in A 1<br />

WT<br />

compared to A 1<br />

KO mouse aorta. S.S. Kunduri, M.A. Nayeem,<br />

J.R. Falck, J. Schnermann and S.J. Mustafa. West Virginia<br />

Univ., Univ. of Texas Southwestern Med. Ctr. and NIDDK, NIH.<br />

C30 958.4 The involvement of PPARa in epoxide-induced<br />

activation of adenosine receptors in angiogenesis. Y.Q. Rizvi,<br />

M. Choi, C. Mehta and A.O. Oyekan. Texas Southern Univ.<br />

959. Role of Nitric Oxide in Vascular<br />

Function<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:30 p m-2:45 p m<br />

C31 959.1 Interaction between sympathomimetic amines,<br />

ephedrine, tyramine and norepinephrine at uptake 1 in<br />

sympathetic nerves and the role of nitric oxide. J.A. Simaan.<br />

American Univ. of Beirut.<br />

C32 959.2 p38 MAPK inhibition prevents angiotensin<br />

II-induced elevation of arginase activity and impaired<br />

vasorelaxation. A. Shatanawi, M.J. Romero, S. Chandra, L.<br />

Yao, H. Flores Toque, J.A. Iddings, R.B. Caldwell and R.W.<br />

Caldwell. Med. Col. of Georgia.<br />

C33 959.3 Mechanisms of AVE3085 against asymmetrical<br />

dimethylarginine-induced endothelial dysfunction. H-M. Xue,<br />

G-W. He, J-H. Huang and Q. Yang. Chinese Univ. of Hong<br />

Kong, Nankai Univ & TEDA Cardiovasc Hosp, Tianjin, People’s<br />

Republic of China and Providence Heart & Vasc. Inst., Oregon<br />

Univ. & Hlth. Sci.<br />

C34 959.4 Peroxynitrite and hydrogen peroxide increase<br />

arginase activity through the RhoA/Rho kinase pathway. S.<br />

Chandra, M.J. Romero, A. Shatanawi, R.B. Caldwell and<br />

R.W. Caldwell. Med. Col. of Georgia.<br />

C35 959.5 Genetic inactivation of endothelial nitric oxide<br />

synthase enhances vasodilator effect of cilostazol. A.V.R.<br />

Santhanam, M.G. Hire, L.A. Smith and Z.S. Katusic. Mayo<br />

Clin. Col. of Med.<br />

C36 959.6 A novel signaling pathway for high output<br />

eNOS-derived nitric oxide in inflamed endothelial cells. J.L.<br />

Lowry, V. Brovkovych, Y. Zhang and R.A. Skidgel. Univ. of<br />

Illinois at Chicago.<br />

C37 959.7 Impaired l-arginine recycling induces<br />

compensatory mechanisms in NO-dependent vessels. R.<br />

Chennupati, B.J.A. Janssen, W.H. Lamers, J.G.R. De Mey<br />

and S.E. Koehler. Maastricht Univ., Netherlands.<br />

C38 959.8 Phosphorylation of endothelial nitric oxide<br />

synthase is increased in mouse model of GTP-cyclohydrolase<br />

I deficiency. L.V. d’Uscio and Z.S. Katusic. Mayo Clin.<br />

C39 959.9 Nitroglycerin reduces TNF-a toxicity to<br />

endothelial cells but compromises the protective effects of<br />

propofol. H-m. Liu, S. Lei, T. Luo, Z-y. Xia, Y. Liu, G.P. Leung,<br />

P.M. Vanhoutte, M.G. Irwin and Z. Xia. Univ. of Hong Kong<br />

and Renmin Hosp., Wuhan Univ., People’s Republic of China.<br />

C40 959.10 Modulation of cyclosporine-induced<br />

hypertension by central endothelial and neuronal nitric oxide<br />

synthases. M.M. El-Mas, A.G. Omar, M.M. Helmy and M.M.<br />

Mohy El-Din. Fac. of Pharm., Univ. of Alexandria, Egypt.<br />

C41 959.11 Pioglitazone ameliorates cyclosporine-induced<br />

attenuation of carbachol renovascular vasodilations: role of<br />

PPARg/nitric oxide synthase signaling. M.M. El-Mas, H.M. El-<br />

Gowelli, E.I. Saad, K.S. Abd-Elrahman and A-G.A. Abdel-<br />

Galil. Fac. of Pharm., Univ. of Alexandria, Egypt.<br />

291<br />

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