Tuesday, april 27 anatomy - Experimental Biology

Physiology
1023. Pulmonary Hypertension: Mechanisms
and Mediators
Poster
Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD
Presentation time: 12:45 p m-3:00 p m
D587 1023.1 Reactive oxygen species-mediated activation
of NFAT leads to pulmonary hypertension. L.V. Gonzalez
Bosc, C. Nitta and J. Friedman. Univ. of New Mexico.
D588 1023.2 Role of glucose-6-phosphate dehydrogenase
in chronic hypoxia-induced pulmonary hypertension. S.
Chettimada, M. Oka, I.F. McMurtry and S.A. Gupte. Univ. of
South Alabama.
D589 1023.3 Bmp2 and Bmp4 exert opposing effects in
hypoxic pulmonary hypertension. M.P. de Caestecker, L.
Anderson, M. Jones and J. Lowery. Vanderbilt Univ.
D590 1023.4 Aberrant eNOS phosphorylation in idiopathic
pulmonary arterial hypertension. S. Ghosh, L. Mavrakis, A.J.
Janocha, S.A.A. Comhair and S.C. Erzurum. Cleveland
Clin.
D591 1023.5 Protein kinase G deficiency induces pulmonary
hypertension in mice and humans. Y-Y. Zhao, M.K. Mirza, S.
Sun, K. Wasiukanis, S.M. Vogel, F. Hofmann and Y. Zhao.
Univ. of Illinois at Chicago and Tech Univ. Munich.
D592 1023.6 Novel role of pre-B-cell colony enhancing
factor in pulmonary arterial hypertension. R.F. Machado,
L. Moreno-Vinasco, E. Chiang, S.R. Zaidi, S. Sammani,
T. Mirzapoiazova, P.T. Toth, M. Ayetkin, R.A. Dweik, S.L.
Archer and J.G.N. Garcia. Univ. of Chicago and Cleveland
Clin. Fndn.
D593 1023.7 The role and regulation of inhibitor of
differentiation family members in hypoxic pulmonary
hypertension. J.W. Lowery, L. Anderson, M. Jones and M.P.
de Caestecker. Vanderbilt Univ.
D594 1023.8 Differential changes of BNIP3 and beclin-1
during the right ventricle response to sustained or intermittent
hypoxia. J. Zhang, A. Joy, Q. Dai, S. Mifflin and M.L. Lindsey.
Univ. of Texas Hlth. Sci. Ctr. at San Antonio and Univ. of North
Texas Hlth. Sci. Ctr.
D595 1023.9 Exercise training has protective effects in
monocrotaline-induced pulmonary hypertension. D. Moreira-
Gonçalves, T. Henriques-Coelho, H. Fonseca, N. Gonçalves,
M. Ferreira-Pinto, M. Dias-Neto, F. Vasques-Novoa, A. Leite-
Moreira and J.A. Duarte. Fac. of Sport and Fac. of Med., Univ.
of Porto, Portugal.
D596 1023.10 Early intervention is important for inhibiting
pulmonary hypertension progression. J-S. Ou, Z-j. Ou, W.
Wei, D-d. Huang, Z-p. Wang and X. Zhang. First Affiliated
Hosp., Sun Yat-sen Univ. and First Municipal People’s Hosp.,
Guangzhou, People’s Republic of China.
D597 1023.11 Effect of digoxin on hypoxic pulmonary
hypertension. E. Abud, C. Undem, J.T. Sylvester, G.L.
Semenza and L.A. Shimoda. Johns Hopkins Sch. of Med.
D598 1023.12 The novel soluble guanylate cyclase activator
PPCA reverses acute hypoxia-induced pulmonary hypertension
in dogs. T. Wang, G.P. McCefferty, C.G. Schnackenberg, B.M.
Jucker, R.N. Willette and D.J. Behm. GlaxoSmithKline.
D599
1023.13 Antenatal maternal hypoxic stress: epigenetic
adaptations in fetal lung renin-angiotensin system. R. Goyal,
A. Leitzke, D. Goyal, C.P. Gheorghe and L.D. Longo. Loma
Linda Univ.
D600 1023.14 Epigenetic programming of pulmonary vascular
dysfunction in mice. E. Rexhaj, C. Sartori and U. Scherrer.
CHUV, Lausanne.
D601 1023.15 In utero hypoxia augments hypoxic pulmonary
vasoconstriction in newborn lamb. S.M. Wilson, D.G.
Papamatheakis, M.R. Terry, T. Merritt, J. Merrill-Henry, H.
Schroeder, L.D. Longo and A.B. Blood. Loma Linda Univ.
Sch. of Med.
D602 1023.16 Synergism between Ca 2+ and Rho-kinase
signaling during pulmonary arterial vasoconstriction in chronic
hypoxic newborn lamb. D.G. Papamatheakis, S. Vemulakonda,
T. Merritt, L.D. Longo, A.B. Blood and S.M. Wilson. Loma
Linda Univ. Sch. of Med.
D603 1023.17 Regulation of vascular smooth muscle
contraction by Ca 2+ signaling and Ca 2+ sensitivity in
intrapulmonary arteries. J.F. Perez-Zoghbi, S. Mukherjee and
M.J. Sanderson. Texas Tech Univ. Hlth. Sci. Ctr. and Univ. of
Massachusetts Med. Sch.
D604 1023.18 ASIC1 mediates enhanced receptor-mediated
vasoconstriction following chronic hypoxia-induced pulmonary
hypertension. N.L. Jernigan, B.R. Walker and T. Resta. Univ.
of New Mexico Hlth. Sci. Ctr.
D605 1023.19 Role of NADPH oxidase in enhanced
membrane depolarization-induced Ca 2+ -sensitization in
pulmonary vascular smooth muscle following chronic hypoxia.
C.E. Norton III, B. Broughton, B.R. Walker and T. Resta. Univ.
of New Mexico.
D606 1023.20 Contribution of mitochondrial reactive oxygen
species to increased pulmonary vasoconstrictor reactivity
following intermittent hypoxia. J. Snow, N. Kanagy, B.R. Walker
and T. Resta. Univ. of New Mexico.
D607 1023.21 Neprilysin peptidase-independent complex
formation in pulmonary artery smooth muscle cells. M.J. Wick,
Y.E. Miller and E.C. Dempsey. Univ. of Colorado Denver,
Aurora and Denver VA Med. Ctr.
D608
1023.22 PDGF-BB signaling in adventitial fibroblasts
during hypoxia-induced pulmonary hypertension. E.
Panzhinskiy, K. Shields, M. Zawada, K. Stenmark and M.
Das. Univ. of Wyoming and Univ. of Colorado Denver, Aurora.
D609
1023.23 Protein kinase A and exchange protein directly
activated by cAMP in human pulmonary artery smooth muscle
cells: expression, function and downstream signaling. O. Kwon,
F. Murray and P.A. Insel. UCSD.
D610
1023.24 Reciprocal regulation of Na + /H + exchanger
isoform 1 and Na + /H + exchange regulatory factor 1 in hypoxic
pulmonary arterial smooth muscle cells. J.A. Maylor, W. Lu, S.
Pisarcik, J. Walker, C. Undem, A.C. Myers and L.A. Shimoda.
Johns Hopkins Univ. Sch. of Med.
D611 1023.25 Characterization of ion channels in progenitor
cells isolated from CTEPH patients. A.L. Firth, O. Platoshyn,
E. Cancino and J.X-J. Yuan. UCSD.
D612 1023.26 Role of caldesmon in hypoxia-mediated
endothelial cell response. A.A. Desai, L. Moreno-Vinasco,
D.S. Parikh, A. Gera and J.G.N. Garcia. Univ. of Chicago.
D613
Tuesday
1023.27 Impact of hyperthyroidism and its correlation on
regional blood flow in rats. D.A. Gomes, C. Mostarda, L. Jorge,
K. De Angelis, M.C. Irigoyen and M.L. Barreto-Chaves. Univ.
of São Paulo and São Judas Tadeu Univ., Brazil.
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