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Tuesday, april 27 anatomy - Experimental Biology

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tuesday<br />

B48 835.10 Characterization of the Thermotoga maritima<br />

ADP-glucose pyrophosphorylase: both glgC and glgD subunits<br />

are required for optimal activity and allosteric regulation. M.<br />

Matsui, E. Guandique, M. Tran, S. Nisperos, A. Orry and<br />

C.R. Meyer. California State Univ., Fullerton and Molsoft LLC,<br />

La Jolla.<br />

B49 835.11 Engineering human paraoxonase-1 double<br />

mutants to hydrolyze organophosphorus compounds. J. Norris,<br />

M. Chung, J.R. Smith and S. Kirby. U.S. Army Med. Res. Inst.<br />

of Chem. Defense, Aberdeen Proving Ground, MD.<br />

B50 835.12 Kinetic characterization of a BCP-class<br />

peroxiredoxin from Escherichia coli. S.A. Reeves, D.<br />

Parsonage, K.J. Nelson and L.B. Poole. Wake Forest Univ.<br />

Sch. of Med.<br />

B51 835.13 Cloning, expression and purification of yeast<br />

aminotransferase. Z.L. Reyes, W.E. Karsten, K.D. Bobyk, P.F.<br />

Cook and L. Chooback. Univ. of Central Oklahoma and Univ.<br />

of Oklahoma.<br />

836. Photochemical Sensors<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:20 p m-1:30 p m<br />

B52 836.1 Measuring readily exchangeable zinc in<br />

Escherichia coli by carbonic anhydrase-based expressible<br />

ratiometric zinc sensor. D. Wang, T.K. Hurst, C.A. Fierke and<br />

R.B. Thompson. Univ. of Michigan and Univ. of Maryland Sch.<br />

of Med.<br />

837. Protease: Structure and Regulation<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:20 p m-1:30 p m<br />

B53 837.1 Identification of a receptor-induced binding site<br />

in plasminogen induced by its interaction with cells. J. Han, R.J.<br />

Parmer and L.A. Miles. The Scripps Res. Inst. and UCSD and<br />

VA San Diego Healthcare Syst.<br />

B54 837.2 Localization and purification of phagosomeassociated<br />

proteases in Tetrahymena thermophila. T. Kaur,<br />

J.R. Carreon and J.W. Straus. Vassar Col. and Ramapo Col.<br />

of New Jersey.<br />

B55 837.3 Enhancing the catalytic activity of an<br />

engineered threonine protease. M. Lansang and T. Baird, Jr.<br />

San Francisco State Univ.<br />

B56 837.4 Introducing extended substrate selectivity into<br />

trypsin through redesign. S.P. Najibi and T. Baird, Jr. San<br />

Francisco State Univ.<br />

B57 837.5 Structural analysis of HIV-1 protease inhibition<br />

using physical models. Lincoln SMART Team, S. Colton, T.<br />

Herman, K. Giles, B. Koo, S. Jeske, N. Ollikainen and J.<br />

Reis. Lincoln H.S., San Francisco, Milwaukee Sch. of Engin.<br />

and UCSF.<br />

B58 837.6 Asn 362 contributes to zinc binding by leukotriene<br />

A 4<br />

hydrolase. M.W. Thompson, A. Schaible and R.L. Seipelt.<br />

Middle Tennessee State Univ.<br />

B59 837.7 Role of the reactive center loop of protein Z<br />

dependent protease inhibitor in determining specificity of the<br />

protease reaction. L. Yang and A.R. Rezaie. Saint Louis Univ.<br />

838. Protein Synthesis, Catalysis and<br />

Turnover<br />

Poster<br />

Biochemistry<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:20 p m-1:30 p m<br />

B60 838.1 Use of RNA affinity chromatography to<br />

investigate factors involved in selenoprotein synthesis and<br />

nonsense decay. M.J. Berry, L. Seale, C.L. Gilman and A.<br />

Seyedali. Univ. of Hawaii at Manoa.<br />

B61 838.2 Covalent modification of proteins by a small<br />

peptide Zfra. N-S. Chang, M-H. Lee and S-R. Lin. ‘Natl. Cheng<br />

Kung Univ. Med. Col., Taiwan and SUNY Upstate Med. Univ.<br />

B62 838.3 Single molecule structural dynamics of<br />

ribosome before and during translocation. B.S. Cooperman,<br />

C. Chen, B. Stevens, H. Liu, D. Cabral, H. Zhang, J. Kaur,<br />

Y. Wang, D. Pan, Z. Smilansky and Y.E. Goldman. Univ. of<br />

Pennsylvania, Univ. of Houston and Anima Cell Metrology Inc.,<br />

Bernardsville, NJ.<br />

B63 838.4 Interrupted catalysis: the EF4 (LepA) effect<br />

on back translocation. H. Liu, D. Pan, M. Pech and B.S.<br />

Cooperman. Univ. of Pennsylvania, Harvard Univ., Boston and<br />

Max Planck Inst. for Molec. Genet., Berlin.<br />

B64 838.5 Signal transduction on the ribosome:timing<br />

EF-Tu release from aminoacyl-tRNA. W. Liu, K. Poruri, W.<br />

Mandecki, Y.E. Goldman and B.S. Cooperman. Univ. of<br />

Pennsylvania and UMDNJ, Newark.<br />

B65 838.6 Facile chemoenzymatic platform for protein<br />

tyrosine-sulfate production. L.Y. Lu, B.H. Chen, J.Y-S. Wu, T.A.<br />

Liu, D.H. Chen, C.C. Wang, T.H. Lin, C.C. Hsu and Y.S. Yang.<br />

Natl. Chiao Tung Univ., Taiwan.<br />

B66 838.7 Generating permissive site-specific unnatural<br />

amino acid synthetases. R.A. Mehl, S.J. Miyake-Stoner and<br />

C.A. Refakis. Franklin & Marshall Col.<br />

B67 838.8 Utilizing elongation factor Tu mutagenesis to<br />

incorporate large unnatural amino acids in vivo. J.C. Peeler<br />

and R.A. Mehl. Franklin & Marshall Col.<br />

B68 838.9 Determination of protein synthesis in vivo with<br />

15<br />

N-glycine labeling and MALDI-TOF spectrum analysis. P.N.<br />

Wahjudi, G.G. Xiao, W.N.P. Lee, M.W. Nowak and N. Shiva.<br />

Los Angeles Biomed. Res. Inst., Creighton Univ. Med. Ctr. and<br />

Endcode Bio Inc. and Proteio Inc., Pasadena.<br />

839. Protein Turnover and Quality Control<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:20 p m-1:30 p m<br />

B69 839.1 Biochemical characterization of the cellular<br />

biosynthesis and trafficking of Caspr2. G. Falivelli, C. Davide,<br />

N. Dubi, A. De Jaco, J. Wilson and P. Taylor. Skaggs Sch. of<br />

Pharm. and Pharmaceut. Sci., UCSD.<br />

B70 839.2 Premature translation termination products are<br />

substrates for the rapidly degraded polypeptide pathway. J.R.<br />

Lacsina, X. Liu and C.V. Nicchitta. Duke Univ. Med. Ctr.<br />

t<br />

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259

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