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Tuesday, april 27 anatomy - Experimental Biology

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tuesday<br />

1026. Control of Breathing: Chemoreception<br />

Poster<br />

Tu e. 7:30 a m—An a h e i m Co n v e n t i o n Ce n t e r, Ex h i b it Ha l l CD<br />

Presentation time: 12:45 p m-3:00 p m<br />

D669 1026.1 Role of pH regulatory components in the<br />

transduction response of central CO 2<br />

chemoreceptors. J.M.<br />

Cordovez, C. Clausen, L.C. Moore and I.C. Solomon. Stony<br />

Brook Univ. and Univ. of los Andes, Colombia.<br />

D670 1026.2 Connexin 26 is responsible for ATP release<br />

underlying central CO 2<br />

chemosensitivity. R.T.R. Huckstepp,<br />

R.C. Eason, R. id Bihi, N. Dicke, K. Willecke, K.M. Spyer,<br />

A.V. Gourine and N. Dale. Warwick Univ., U.K., Univ. of Bonn<br />

and University Col. London.<br />

D671 1026.3 The bullfrog neuroventilatory response to<br />

hypercapnia is unaffected by cannabinergic potentiation. N.B.<br />

Bajada, C.M. Brundage and B.E. Taylor. Univ. of Alaska<br />

Fairbanks.<br />

D672 1026.4 Leptin deficiency impairs hypercapnic<br />

ventilatory responses independently of changes in body weight.<br />

M. Bassi, J.M. do Carmo, S. Hamza and J.E. Hall. Univ. of<br />

Mississippi Med. Ctr.<br />

D673 1026.5 Modulation of neuroventilation and central<br />

chemosensitivity: serotonergic and hypocretinergic effects.<br />

A.E. Corcoran, G.B. Richerson and M.B. Harris. Dartmouth<br />

Med. Sch., Yale Univ. and Univ. of Alaska Fairbanks.<br />

D674 1026.6 Chronic administration of fluoxetine markedly<br />

attenuates the hypercapnic ventilatory response in urethaneanesthetized<br />

female mice. T.A. Bale and I.C. Solomon. Stony<br />

Brook Univ.<br />

D675 1026.7 Raphe serotonin neurons: characteristics of<br />

central chemoreceptors in situ. K.E. Iceman, A.E. Corcoran<br />

and M.B. Harris. Univ. of Alaska Fairbanks and Dartmouth<br />

Med. Sch.<br />

D676 1026.8 The orexin receptor 1 in the rostral medullary<br />

raphe contributes to the hypercapnic chemoreflex in<br />

wakefulness, during the dark (active) period of the diurnal<br />

cycle. M.B. Dias, A. Li and E.E. Nattie. Dartmouth Med. Sch.<br />

D677 1026.9 Effects of bilateral inhibition of retrotrapezoid<br />

nucleus on breathing in conscious rats. A.C. Takakura, T.S.<br />

Moreira, P.M. De Paula, J.V. Menani and E. Colombari. São<br />

Paulo State Univ., Araraquara, Univ. of São Paulo and Fed.<br />

Univ. of São Paulo.<br />

D678 1026.10 Photostimulation of channelrhodopsintransfected<br />

rostral medullary Phox2b-expressing neurons<br />

activates breathing in unaesthetized rats. R. Kanbar, R.L.<br />

Stornetta, S.J. Lewis and P.G. Guyenet. Univ. of Virginia.<br />

D679 1026.11 Changes on respiratory chemosensitivity after<br />

vagotomy in rats. T.S. Moreira and A.C. Takakura. Univ. of São<br />

Paulo and São Paulo State Univ., Araraquara.<br />

D680 1026.12 Focal acidification of the caudal ventrolateral<br />

medulla (Loeschcke’s area) increases ventilation during<br />

wakefulness but not in sleep. G.S.F. Silva, A. Li and E. Nattie.<br />

Dartmouth Med. Sch.<br />

D681<br />

1026.13 NK-1 receptors expressing neurons in the locus<br />

coeruleus play a role in cardiorespiratory response to CO 2<br />

. L.H.<br />

Gargaglioni, D. de Carvalho, K.C. Bicego, G.S. Ferreira da<br />

Silva, O.W. Castro and N. Garcia-Cairasco. FCAVJ-São Paulo<br />

State Univ. and FMRP-Univ. of São Paulo, Ribeirão Preto.<br />

pHysiology<br />

D682 1026.14 Further evidence of redox modulation of<br />

neurons in a CO 2<br />

-chemosensitive area: normobaric hyperoxia<br />

(95%O 2<br />

) stimulates CO 2<br />

-chemosensitive and –insensitive<br />

neurons in the solitary comple. M.P. Matott, C.S. Landon,<br />

R.W. Putnam and J.B. Dean. Univ. of South Florida and Wright<br />

State Univ.<br />

D683 1026.15 The effect of hypoxia on the ventilatory and<br />

cerebral blood flow responses to CO 2<br />

. A. Battisti, J. Fisher<br />

and J. Duffin. Univ. of Toronto and Toronto Gen. Hosp.<br />

D684 1026.16 Oxygen transport from air to cell: the impact of<br />

age. M. Amann, D.W. Wray, C. Wary, A. Monnet, P.G. Carlier<br />

and R.S. Richardson. Univ. of Utah, Pitié-Salpêtrière Univ.<br />

Hosp., Paris and VA Med. Ctr., Salt Lake City.<br />

D685 1026.17 Baroreflex unloading blunts chemoreceptor<br />

sensitivity in postural tachycardia syndrome. I. Taneja, D.A.<br />

Clarke, M.S. Medow, A.J. Ocon and J.M. Stewart. New York<br />

Med. Col.<br />

D686 1026.18 Prolonged maintenance of cardiopulmonary<br />

stability in mice: strain-specific ventilatory requirements. L.<br />

Pichard, E. Kostuk, P. Pashai, R. Fitzgerald and M. Shirahata.<br />

Johns Hopkins Univ.<br />

D687 1026.19 Murine carotid body responses to hypoxia:<br />

in vivo carotid sinus nerve recordings in the DBA/2J and A/J<br />

strains. L. Pichard, F. Sgambati, E. Kostuk, P. Bashai, R.<br />

Fitzgerald and M. Shirahata. Johns Hopkins Univ.<br />

D688 1026.20 Global knockout of AMP-activated protein<br />

kinase alpha subunits attenuates the hypoxic ventilatory<br />

response in mice. C.N. Wyatt, H.L. Jordan, B.L. Barr, B.<br />

Viollet, C. Peers, D.G. Hardie and A.M. Evans. Wright State<br />

Univ., INSERM, Paris, Leeds Univ., Univ. of Dundee and Univ.<br />

of Edinburgh.<br />

D689 1026.21 In vivo pharmacological alterations of murine<br />

carotid body responses to hypoxia: the role of BK channels<br />

in hypoxic sensitivity. L. Pichard, F. Sgambati, E. Kostuk,<br />

P. Bashai, R. Fitzgerald and M. Shirahata. Johns Hopkins<br />

Univ.<br />

D690 1026.22 Hypoxia versus hydrogen sulfide acting at the<br />

carotid body and elsewhere systemically. R.S. Fitzgerald, M.<br />

Shirahata and E. Kostuk. Johns Hopkins Univ.<br />

D691 1026.23 Effects of HIF-1a gene deletion in respiratory<br />

centers on ventilatory acclimatization to hypoxia. A. Go, Z. Fu,<br />

R.S. Johnson and F.L. Powell. UCSD.<br />

D692 1026.24 The effect of chronic ibuprofen treatment on<br />

ventilatory acclimatization to hypoxia. D. Popa, Z. Fu and F.<br />

Powell. UCSD.<br />

D693 1026.25 Chronic sustained hypoxia reduces neuronal<br />

excitability in 2nd-order neurons of peripheral chemoreceptors<br />

in the NTS. W. Zhang and S. Mifflin. Univ. of North Texas Hlth.<br />

Sci. Ctr. at Fort Worth.<br />

D694 1026.26 Activation of adenosine A2A receptor<br />

on GABAergic inputs to 2nd-order neurons of peripheral<br />

chemoreceptors in the NTS. W. Zhang and S.W. Mifflin. Univ.<br />

of North Texas Hlth. Sci. Ctr. at Fort Worth.<br />

D695 1026.<strong>27</strong> Developmental regulation of glucosensing in<br />

rat adrenomedullary chromaffin cells. S.J. Livermore, N.A.<br />

Piskuric, J.A. Buttigieg and C.A. Nurse. McMaster Univ.,<br />

Canada and Toronto Western Hosp.<br />

D696 1026.28 Intermittent hypoxia enhances chemical<br />

sensitivity of pulmonary C fibers in rats: role of reactive oxygen<br />

species. M-Y. Shen, Y-L. Luo and C.J. Lai. Tzu Chi Univ.,<br />

Taiwan.<br />

t<br />

u<br />

e<br />

323

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