Pesticide Analyzer Reference - writeframeofmind.biz

SRM Method Library
SRM Method Library
For the quantitation and confirmation of pesticides by GC-MSMS, the acquisition mode of Selected Reaction Monitoring (SRM or MRM - multiple reaction
monitoring) is used. With the TSQ Quantum GC mass spectrometer, our unique H-SRM (highly selective reaction monitoring) mode is available. Because of
its highly resolved precursor ion selection, most of the accompanying matrix can be cut from the collision cell and very high signal-to-noise peak detection can
be performed.
The H-SRM mode of the TSQ Quantum GC mass spectrometer operates at optimum selectivity using precise precursor masses. For that purpose, all masses
of precursors and product ions are listed in the table below with two decimals for unsurpassed matrix selectivity. Also in the table below, Exact Mass refers to
the mass of the monoisotopic M and Mass Defect refers to the difference between the exact mass and nominal mass normalized to 100 Da.
The collision energies are empirically determined values. Typically, low collision energies are preferred for generating a single intense product ion. In
compliance with international regulations, two product-to-product ion transitions are used for quantitation and confirmation with the ion ratio.
For many compounds, monitoring of more than two transitions is listed. This flexibility allows you to react to unexpected matrix interferences. The optimum
transitions for a given matrix can be selected in QuanLab Forms data reprocessing software in the local processing method.
Thermo Scientific Pesticide Analyzer Reference 93