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The Natural Repertory of Prof. William Nelson

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In 1986, Carl Popper delivered an address to the Royal Society. In this<br />

address he told the attendees, who included many <strong>of</strong> the fathers <strong>of</strong><br />

synthetic molecular biology, that biochemical organizations and<br />

processes could never be understood in chemical terms alone. Because <strong>of</strong><br />

this, Popper proposed that organic evolution would never be explained by<br />

chemical or Darwinian <strong>The</strong>ory and that chemical reductionism for the<br />

environment proposed many different risks, as we put many <strong>of</strong> these<br />

synthetic chemicals into our environment and our bodies. In fact, due to<br />

the large number <strong>of</strong> chemicals which have been put into our bodies,<br />

perhaps Carl Popper’s warning has come too late. Many dramatic<br />

problems have resulted from iatrogenic poisoning <strong>of</strong> the planet and<br />

iatrogenic diseases which were caused by synthetic compounds.<br />

Dramatic damage has resulted from ignorance and pr<strong>of</strong>iteering.<br />

Man’s ability to understand is always limited by his ability to measure<br />

the results <strong>of</strong> his work. At every point in science the scientists assume<br />

that their measurements are complete, therefore their knowledge must<br />

be complete. As new discoveries are made and more sophisticated<br />

measurement techniques are developed this philosophy opens the door<br />

to deeper and deeper understanding. With the advent <strong>of</strong> quantum theory<br />

and the idea <strong>of</strong> the Heisenberg Uncertainty Principle we now realize that<br />

true knowledge cannot be attained, and that we cannot in any way<br />

manufacture the same compounds developed by nature. Our attempts at<br />

this are merely guesses, perhaps good guesses but still, nature holds<br />

secrets as we continue to explore biology to the end <strong>of</strong> our days. Only<br />

nature truly knows.<br />

In 1893, Albrecht Kossel, doing physiological research identified<br />

chromatin as a nucleoprotamine. This was found to be a nucleoprotein,<br />

and was some <strong>of</strong> the beginning work needed in looking at RNA and DNA<br />

function.<br />

Nucleic acid sugars and their phosphate-bonded brothers were written<br />

about by Phoebus Levene in 1905. Levene, working with Walter A.<br />

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