17.11.2012 Views

The Natural Repertory of Prof. William Nelson

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Summary <strong>of</strong> Immunopathology, Histopathology, and Electron-microscopic findings <strong>of</strong> the Kidney in Snakebite<br />

Histopathology Electron-microscopy<br />

Immunopathology<br />

Location <strong>of</strong> deposits<br />

Arteriolar Arterial Proliferation Tubular Necrotizing Thrombophlebitis Glomerular Glomerular Tubular<br />

wall wall <strong>of</strong> glomerular necrosis and arteritis<br />

electron- basement degeneration,<br />

mesangial regeneration<br />

dense membrane necrosis and<br />

cells<br />

deposits alteration regeneration<br />

C3(=) C3(+) + ++ + + + - +<br />

Glomerular<br />

capillary<br />

Type <strong>of</strong><br />

Snake<br />

1gM<br />

(+ to ++)<br />

Russell’s<br />

viper<br />

C3(=)<br />

+ to ++ + - + + b - +<br />

C3(=) No<br />

deposit<br />

1gM (trace to<br />

+)<br />

C3(=)<br />

Green<br />

pit viper<br />

Fibrin a<br />

+ - - - + + -<br />

C3 (=) No<br />

deposit<br />

1gM (+)<br />

C3<br />

Cobra<br />

(+ to ++)<br />

- = Negative<br />

+ = Mild<br />

++ = Moderate<br />

a<br />

= Focal deposition<br />

b<br />

= With deposition <strong>of</strong> fibrin<br />

255

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