Fact Sheets on Antiretroviral Drugs
Fact Sheets on Antiretroviral Drugs
Fact Sheets on Antiretroviral Drugs
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<str<strong>on</strong>g>Fact</str<strong>on</strong>g> <str<strong>on</strong>g>Sheets</str<strong>on</strong>g> <strong>on</strong> <strong>Antiretroviral</strong> <strong>Drugs</strong><br />
Page 46<br />
Side Effects Frequency Severity<br />
Diarrhoea +++ +<br />
Rash + +/-<br />
Nausea + +/-<br />
Asthenia + +/-<br />
Flatulence + +/-<br />
Abdominal pain +/- +/-<br />
Rit<strong>on</strong>avir (RTV)<br />
Class<br />
Protease Inhibitor (PI)<br />
Available formulati<strong>on</strong>s<br />
Storage<br />
Dose<br />
� Oral soluti<strong>on</strong>: 80 mg/ml<br />
� Capsules: 100 mg<br />
� Capsules should be refrigerated until dispensed; then, they are stable at<br />
room temperature for 30 days.<br />
� Room temperature for oral soluti<strong>on</strong> (do not refrigerate)<br />
Adults: WHO recommends to use Rit<strong>on</strong>avir <strong>on</strong>ly as booster for other<br />
PIs at low dosage<br />
Possible dose if used al<strong>on</strong>e: 600 mg (6 caps.) twice daily<br />
Children: 400 mg/m2 of body surface every 12 hours
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