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Fact Sheets on Antiretroviral Drugs

Fact Sheets on Antiretroviral Drugs

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<str<strong>on</strong>g>Fact</str<strong>on</strong>g> <str<strong>on</strong>g>Sheets</str<strong>on</strong>g> <strong>on</strong> <strong>Antiretroviral</strong> <strong>Drugs</strong><br />

not been definitively established, although the risk appears higher in patients receiving<br />

PI than n<strong>on</strong>-PI-c<strong>on</strong>taining regimens.<br />

However, a recent study showed that men receiving protease inhibitors had a<br />

higher incidence of osteopenia and osteoporosis according to WHO definiti<strong>on</strong>s.<br />

Subjects receiving protease inhibitors had greater central/appendicular adipose tissue<br />

ratios than patients not receiving PIs. Furthermore, osteopenia and osteoporosis are<br />

unique metabolic complicati<strong>on</strong>s that appear to be independent of adipose tissue<br />

maldistributi<strong>on</strong>.<br />

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