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Abstracts of the Academy of Dental Materials Annual ... - IsiRed

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sectioned, placed into 50% (w/v) ammoniacal silver nitrate<br />

solution for 24 h, exposed to photodeveloping solution and<br />

observed using SEM. Percentage distribution <strong>of</strong> metallic silver<br />

particles in <strong>the</strong> resin/dentin interface was calculated using<br />

digital image analysis s<strong>of</strong>tware. Shrinkage stresses and stress<br />

rates <strong>of</strong> resin composites were measured continuously from<br />

start <strong>of</strong> light curing and up to 30 min using a Tensometer testing<br />

machine (NIST, Gai<strong>the</strong>rsburg, MD). Data were analyzed by<br />

one-way ANOVA followed by a Tukey multiple comparisons<br />

test. (p < 0.05).<br />

Results: Increasing C-factor did not affect <strong>the</strong> nanoleakage<br />

<strong>of</strong> low shrinkage composites, meanwhile silver nitrate depositions<br />

were significantly increased in high C-factor cavities in<br />

<strong>the</strong> control group. Mean maximum shrinkage stresses results<br />

were 0.94 ± 0.1, 1.79 ± 0.18 and 2.14 ± 0.23 MPa for SIL, AL and<br />

Z, respectively.<br />

Conclusion: Using low shrinkage composites in cavities<br />

with high C-factor may be an alternative to avoid <strong>the</strong> deteriorating<br />

effect <strong>of</strong> increasing <strong>the</strong> C-factor on <strong>the</strong> bond <strong>of</strong> resin<br />

composite to dentin.<br />

doi:10.1016/j.dental.2010.08.065<br />

58<br />

Can filler-size affect <strong>the</strong> colour and gloss <strong>of</strong> resin-composites?<br />

H. Elbishari, J. Satterthwaite, Nick Silikas<br />

School <strong>of</strong> Dentistry, University <strong>of</strong> Manchester, United Kingdom<br />

Objectives: To study <strong>the</strong> effect <strong>of</strong> filler size on <strong>the</strong> colour<br />

change and gloss over time in three different storage media.<br />

<strong>Materials</strong> and methods: Disc shaped specimens<br />

(2 mm × 10 mm) prepared and polished using OptiDisc<br />

(Kerr <strong>Dental</strong>). Samples allocated to 4 groups (n = 12) according<br />

to <strong>the</strong>ir filler size. Gloss and colour measured with a<br />

Novocurve glossmeter and Minolta colourmeter, respectively,<br />

and <strong>the</strong>n stored in three media (water, cola and red wine).<br />

Measurements for gloss and colour were <strong>the</strong>n recorded 24 h,<br />

2 weeks and 3 months, respectively. Data was analysed with<br />

one-way ANOVA (SPSS, 16.0).<br />

Results: Filler distribution resulted in significant changes in<br />

colour (�E). �E values ranged from 1.6 to 15.6 and gloss from<br />

89.6 to 51.3. In all cases <strong>the</strong> trimodal filler distribution, that<br />

incorporated small size nan<strong>of</strong>illers (100 nm), resulted in <strong>the</strong><br />

least colour change. All materials had high initial gloss values.<br />

Storage media affected gloss and <strong>the</strong>re was a gloss reduction<br />

with all storage media. Red wine had <strong>the</strong> highest reduction in<br />

gloss values.<br />

Conclusions: Filler size and distribution had a significant<br />

effect on <strong>the</strong> aes<strong>the</strong>tic properties (colour and gloss) <strong>of</strong> resincomposites.<br />

Storage media and storage time also significantly<br />

affected <strong>the</strong>se properties. Prolonged storage time resulted in<br />

<strong>the</strong> highest changes.<br />

doi:10.1016/j.dental.2010.08.066<br />

dental materials 26S (2010) e1–e84 e27<br />

59<br />

Choosing <strong>the</strong> allocation method for clinical trials in restorative<br />

dentistry<br />

H. Fron 1 , P. Durieux 2 , G. Chatellier 2 , F. Gillaizeau 2 , J.P. Attal 1<br />

1 URB2I, Université Paris Descartes, France<br />

2 APHP HEGP; INSERM, UMR S 872/20, France<br />

Objectives: Treatment allocation in restorative trials is<br />

generally defined by pre-set random tables. However, this<br />

method does not account for prognostic factors <strong>of</strong> <strong>the</strong> restorations<br />

and does not respect allocation concealment, so that<br />

treatment groups are not comparable and conclusions are<br />

biased, especially because <strong>the</strong> groups are small-sized. Comparable<br />

groups are obtained by optimizing balance between<br />

groups and limiting allocation predictability. Two methods<br />

could be used in restorative dentistry to achieve comparability:<br />

blocked randomization and minimization. Blocked randomization<br />

consists in using a separate randomization list for each<br />

prognostic group. Minimization is an adaptive method that<br />

minimizes <strong>the</strong> imbalance between <strong>the</strong> number <strong>of</strong> patients in<br />

each treatment group over a number <strong>of</strong> prognostic factors. The<br />

purpose <strong>of</strong> this study was to choose between <strong>the</strong>se two methods<br />

for a randomized controlled trial comparing ceramic and<br />

composite CAD-CAM inlays.<br />

<strong>Materials</strong> and methods: A Visual Basic for applications<br />

program was computed. 1000 sets <strong>of</strong> 350 patients were simulated<br />

according to <strong>the</strong> proportions expected for each <strong>of</strong><br />

<strong>the</strong> four main predictive factors (inlay/onlay, premolar/molar,<br />

vital/non vital tooth, operator). These patients were allocated<br />

by minimization with a varying random element and stratification<br />

with blocks <strong>of</strong> 2 and 4. Allocation methods were<br />

compared in terms <strong>of</strong> predictability and balance.<br />

Results: The balance obtained with blocked randomization<br />

was better than expected, although minimization proved to<br />

better account for balance and predictability at <strong>the</strong> same time.<br />

Minimization with a random element <strong>of</strong> 30% achieved <strong>the</strong> lowest<br />

imbalance (0.51% <strong>of</strong> <strong>the</strong> sample size) and predictability<br />

(52.68% when operator remembered his three last allocations).<br />

Conclusions: Minimization with a 30% random element<br />

allowed accounting for four prognostic factors in <strong>the</strong> planned<br />

clinical trial and achieving excellent group comparability. Simulations<br />

help decide which allocation method is best for a<br />

clinical trial in restorative dentistry.<br />

doi:10.1016/j.dental.2010.08.067<br />

60<br />

Polishability <strong>of</strong> nan<strong>of</strong>illed resin-based composites<br />

K. Hirata, J. Yamagawa # , S. Geraldeli ∗ , F. Qian, S.R. Armstrong<br />

The University <strong>of</strong> Iowa, USA<br />

Objectives: To evaluate baseline laboratory-grade polishability<br />

<strong>of</strong> six resin-based composites (RBC) in preparation for<br />

polish retention and surface roughness evaluation.<br />

# at time <strong>of</strong> participation in <strong>the</strong> research at The University <strong>of</strong><br />

Iowa, J. Yamagawa was an employee <strong>of</strong> Tokuyama <strong>Dental</strong><br />

Corporation. Study sponsored by Tokuyama.

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