Analysis of genome-scale count data in Bioconductor
Analysis of genome-scale count data in Bioconductor
Analysis of genome-scale count data in Bioconductor
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Common dispersion model• One approach: use same value forthe dispersion for all genes• Estimate us<strong>in</strong>g all genes <strong>in</strong> <strong>data</strong>set(conditional max likelihood)• Produces a reliable estimate• Nice biological <strong>in</strong>terpretation, but canbe heavy handed