Analysis of genome-scale count data in Bioconductor
Analysis of genome-scale count data in Bioconductor
Analysis of genome-scale count data in Bioconductor
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B<strong>in</strong>omial exact test<strong>in</strong>gobserved• Poisson model: sum <strong>of</strong> Poisson RVs is a Poisson RV• Conditional distribution (on total sum for a gene) is mult<strong>in</strong>omial• Two groups: can compute exact p-value for DE from b<strong>in</strong>omialdistribution